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115-90-2

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Basic Information
CAS No.: 115-90-2
Name: Fensulfothion
Article Data: 2
Molecular Structure:
Molecular Structure of 115-90-2 (Fensulfothion)
Formula: C11H17O4PS2
Molecular Weight: 308.359
Synonyms: Phosphorothioicacid, O,O-diethyl O-[p-(methylsulfinyl)phenyl] ester (6CI,7CI,8CI);Agricur;B25141;BAY 25141;Chemagro 25141;Daconit;Dasanit;ENT 24,945;
EINECS: 204-114-3
Density: 1.312 g/cm3
Melting Point: 25°C
Boiling Point: 404.032 °C at 760 mmHg
Flash Point: 198.152 °C
Solubility: 1.54g/L(25 oC)
Appearance: oily yellow or brown liquid
Hazard Symbols: VeryT+, DangerousN
Risk Codes: 27/28-50/53
Safety: 23-28-36/37-45-60-61
Transport Information: UN 3018
PSA: 105.87000
LogP: 4.61660
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Consensus Reports

EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List.

Standards and Recommendations

OSHA PEL: TWA 0.1 mg/m3
ACGIH TLV: TWA 0.1 mg/m3; Not Classifiable as a Human Carcinogen

Specification

 Fensulfothion ,with its CAS Registry Number 115-90-2, its IUPAC Name is Diethoxy-(4-methylsulfinylphenoxy)-sulfanylidene-λ5-phosphane . It is also named as Chemagro 25141 ; Daconit ; Dasanit ; Diethyl p-methylsulfinylphenyl thiophosphate ; O,O-Diaethyl-O-(4-methylsulfinyl-phenyl)-thionophosphat ; Phenol, p-(methylsulfinyl)-, O-ester with O,O-diethyl phosphorothioate . And Fensulfothion is a yellow-brown liquid storge at room temperature which is  0-6 °C and is relatively stable. Besides, it is slightly soluble in water and can hydrolyze in alkali, isomerize in air. So it is incompatible with alkali chemicals.

 Organothiophosphates, such as Fensulfothion , are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Furthermore, Fensulfothion was used against soil nematodes and a broad spectrum of soil-borne insects in field crops, vegetables and fruit. It is also used against nematodes in turf grasses, flowers and ornamental plants. 

  Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. In additon, Fensulfothion displays cholinesterase inhibiting properties. Death results primarily from respiratory arrest stemming from failure of the respiratory center, paralysis of respiratory muscles and intense bronchoconstriction. And Fensulfothion may burn but may not ignite readily. Containers may explode in heat of fire. Toxic fumes of phosphorus and sulfur oxides are emitted when heated highly. The toxicity of Fensulfothion as follow:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 240ug/kg (0.24mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
bird - wild LD50 skin 420ug/kg (0.42mg/kg)   Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973.
duck LD50 oral 747ug/kg (0.747mg/kg)   Toxicology and Applied Pharmacology. Vol. 22, Pg. 556, 1972.
duck LD50 skin 3mg/kg (3mg/kg)   Toxicology and Applied Pharmacology. Vol. 47, Pg. 451, 1979.
guinea pig LD50 intraperitoneal 5400ug/kg (5.4mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 78, 1964.
guinea pig LD50 oral 9mg/kg (9mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 78, 1964.
mouse LD50 intracrebral 2mg/kg (2mg/kg)   Pesticide Biochemistry and Physiology. Vol. 8, Pg. 302, 1978.
mouse LD50 intraperitoneal 7mg/kg (7mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 78, 1964.
pigeon LD50 oral 560ug/kg (0.56mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail LD50 oral 1200ug/kg (1.2mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Ecotoxicology and Environmental Safety. Vol. 8, Pg. 551, 1984.
rat LC50 inhalation 113mg/m3/1H (113mg/m3)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A202, Pg. 1983,
rat LD50 intraperitoneal 1500ug/kg (1.5mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 78, 1964.
rat LD50 oral 2200ug/kg (2.2mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 78, 1964.
rat LD50 skin 3mg/kg (3mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat LD50 unreported 11mg/kg (11mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 337, 1971.