121-75-5

IUPAC Name: diethyl 2-dimethoxyphosphinothioylsulfanylbutanedioate 
Empirical Formula: C₁₀H₁₉O₆PS₂
Molecular Weight: 330.358g/mol
EINECS: 204-497-7 
Structure of Malathion (CAS NO.121-75-5):

Index of Refraction: 1.508
Molar Refractivity: 77.5 cm³
Molar Volume: 259.6 cm³
Polarizability: 30.72×10^-24cm³
Surface Tension: 47.1 dyne/cm
Density: 1.272 g/cm³
Flash Point: 186.7 °C
Enthalpy of Vaporization: 63.39 kJ/mol 
Melting point: 2.85 ºC
Boiling Point: 385.1 °C at 760 mmHg
Vapour Pressure: 3.9E-06 mmHg at 25°C 
Water solubility: 0.0145 g/100 mL 
Stability: Stable. Incompatible with oxidizing agents, metals. 
Product Categories: Metal Isotopes;INSECTICIDE;Sulfur & Selenium Compounds;2000/60/ECMore...Close...;Alpha sort;Endocrine Disruptors (Draft)Pesticides&Metabolites;H-MAlphabetic;MA -MDPesticides;2000/60/EC;AcaricidesMethod Specific;Endocrine Disruptors (Draft)Alphabetic;EPA;European Community: ISO and DIN;Insecticides;M;OrganophorousMethod Specific;Pesticides;Pesticides&Metabolites 
Canonical SMILES: CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC
InChI: InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3
InChIKey: JXSJBGJIGXNWCI-UHFFFAOYSA-N

 Malathion (CAS NO.121-75-5) is a pesticide that is widely used in agriculture, residential landscaping, public recreation areas, and in public health pest control programs such as mosquito eradication. In the US, it is the most commonly used organophosphate insecticide. Malathion has also been used to combat the Mediterranean Fruit Fly in Australia. Malathion was sprayed in many cities to combat West Nile virus. And it is also used in conjunction with diesel fuel to fog an area where there is an infestation of mosquitoes. Malathion in low doses (0.5% preparations) can be used as a treatment for head lice, body lice, and scabies.It is one of the very popular, short-lived broad-spectrum insecticides for application to nearly all fruits, vegetables, field crops, dairy livestock, and household insects.

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal No Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 30 ,1983,p. 103.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-24 ,1978. ; No Evidence: rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-192 ,1979. . EPA Genetic Toxicology Program.

A human poison by ingestion and skin contact. Can penetrate intact skin. An experimental poison by ingestion, inhalation, intraperitoneal, intravenous, intraarterial, and subcutaneous routes. Human systemic effects by ingestion: coma, blood pressure depression, and difficulty in breathing. Questionable carcinogen. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. Has caused allergic sensitization of the skin. An organic phosphate cholinesterase inhibitor. When heated to decomposition it emits toxic fumes of PO_x and SO_x. See also PHOSPHATES and PARATHION.
Hazard Codes: Xn;N;F
Risk Statements: 22-50/53-67-65-38-11
22:  Harmful if swallowed 
50/53:  Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment 
67:  Vapors may cause drowsiness and dizziness 
65:  Harmful: May cause lung damage if swallowed 
38:  Irritating to the skin 
11:  Highly Flammable
Safety Statements: 2-24-60-61-62
2:  Keep out of the reach of children 
24:  Avoid contact with skin 
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 
62:  If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label
RIDADR:  UN 2783
HazardClass:  6.1(b)

OSHA PEL: TWA Total Dust: 10 mg/m³; Respirable Fraction: 5 mg/m³ (skin)
ACGIH TLV: TWA 1 mg/m³ (skin); Not Classifiable as a Human Carcinogen
DFG MAK: 15 mg/m³
NIOSH REL: (Malathion) TWA 15 mg/m³

 Malathion , its cas register number is 121-75-5. It also can be called  ((Dimethoxyphosphinothioyl)thio)butanedioic acid diethyl ester ; American cyanamid 4,049 ; Butanedioic acid, ((dimethoxyphosphinothioyl)thio)-, diethyl ester ; Camathion ;
 Carbethoxy malathion ; Dicarboethoxyethyl O,O-dimethyl phosphorodithioate ; Dorthion ; Ethiolacar ; Forthion ; Hilthion ;
Karbofos ; Malacide ; Mercaptosuccinic acid diethyl ester ; O,O-Dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl) dithiophosphate ;
 Oleophosphothion ; Paladin ; Phosphorodithioic acid, O,O-dimethyl ester, S-ester with diethyl mercaptosuccinate ; S-(1,2-Bis(carbethoxy)ethyl) O,O-dimethyl dithiophosphate ; Sadophos ; Succinic acid, mercapto-, diethyl ester, S-ester with O,O-dimethyl phosphorodithioate ; Sumitox . Malathion (CAS NO.121-75-5) is a deep brown to yellow liquid