CAS No.122384-88-7,AMYLIN, HUMAN Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	122384-88-7
Name:	AMYLIN, HUMAN

Formula:	C₁₆₅H₂₆₁N₅₁O₅₅S₂
Molecular Weight:	3903.31
Synonyms:	1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane,cyclic peptide deriv;AC 001;Amlintide;Amylin (human);Diabetes-associatedpeptide (human);Human IAPP;Human amylin;Human islet amyloid peptide;Amylin, Human, Amide;L-Tyrosinamide,L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-,cyclic (2®7)-disulfide;Amlintide [USAN:INN];L-Lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-L-tyrosinamide, cyclic (2-7)-disulfide;L-Tyrosinamide, L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-, cyclic (2-7)-disulfide;
Solubility:	dissolved in DMSO or DMF first and then dilute with water
PSA:	1808.07000
LogP:	-5.38340

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Chemistry

The Molecular Structure of Diabetes-associated peptide amide human (CAS NO.122384-88-7):

Molecular Weight: 3903.31
Molecular Formula: C₁₆₅H₂₆₁N₅₁O₅₅S₂
Solubility: it can be dissolved in DMSO or DMF first and then dilute with water.
Storage: Store at -20°C.Keep container tightly closed. Store in a cool dry place.
Synonyms: Amlintide [USAN:INN] ; AC 001 ; Amlintide ; Amylin (human) ; Human islet amyloid peptide ; UNII-U3U3114NE1 ; L-Lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-L-tyrosinamide, cyclic (2-7)-disulfide ; L-Tyrosinamide, L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-, cyclic (2-7)-disulfide .

Specification

Diabetes-associated peptide amide human (CAS NO.122384-88-7) that is structurally related to calcitonin, is secreted from the B cells of the pancreas. It has anoretic effects in rats. Diabetes-associated peptide amide human (CAS NO.122384-88-7) may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin .