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CAS No.: | 1256580-46-7 |
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Name: | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile |
Article Data: | 22 |
Molecular Structure: | |
Formula: | C30H34N4O2 |
Molecular Weight: | 482.62 |
Synonyms: | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile; |
EINECS: | 821-541-6 |
Density: | 1.28 |
Boiling Point: | 722.5±60.0 °C(Predicted) |
PSA: | 72.36000 |
LogP: | 4.77618 |
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CH5424802 is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. CH5424802 have been clinically evaluated for the treatment of patients with ALK-driven tumors.