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136-16-3

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Basic Information
CAS No.: 136-16-3
Name: OXYTHIAMINE HYDROCHLORIDE
Molecular Structure:
Molecular Structure of 136-16-3 (OXYTHIAMINE HYDROCHLORIDE)
Formula: C12H16 N3 O2 S
Molecular Weight: 266.37
Synonyms: Thiazolium,3-[(1,4-dihydro-2-methyl-4-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-(9CI); Thiazolium,5-(2-hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methyl-(8CI); 4'-Oxythiamin; Hydroxythiamin; Oxythiamin; Oxythiamine
Density: g/cm3
Boiling Point: °Cat760mmHg
Flash Point: °C
Safety: Moderately toxic by subcutaneous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.
PSA: 98.36000
LogP: -1.46290
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    OXYTHIAMINE HYDROCHLORIDE

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    factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

    Zhejiang Jiuzhou Chemical Co.,Ltd is a market-oriented and innovation-driven biopharmaceutical company. The company is focusing on the R&D, manufacturing and sales of pharmaceutica

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  • OXYTHIAMINE HYDROCHLORIDE

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    OXYTHIAMINE HYDROCHLORIDE

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    Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

    Shanghai fine pharma co., Ltd. is a professional enterprise with chemical reagents and fine chemical products development, development and trade. The company has a sound research a

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Chemistry

Chemistry informtion about Oxythiamine (CAS NO.136-16-3) is:
IUPAC Name: 5-[[5-(2-Hydroxyethyl)-4-Methyl-1,3-Thiazol-3-Ium-3-Yl]Methyl]-2-Methyl-1H-Pyrimidin-6-One Chloride
Synonyms: Thiazolium,5-(2-Hydroxyethyl)-3-((4-Hydroxy-2-Methyl-5-Pyrimidinyl)Methyl)-4-M ; 5-(2-Hydroxyethyl)-3-(4-Hydroxy-2-Methyl-5-Pyrimidinylmethyl)-4-Methylthiazolium Chloride ; 5-[2-Hydroxyethyl]-3-[4-Hydroxy-2-Methyl-5-Pyrimidinylmethyl]-4-Methylthiazolium Chloride Hydrochloride ; Oxythiamine Chloride Hydrochloride ; Oxythiamine Hcl ; Oxythiamine Hydrochloride ; 5-(2-Hydroxyethyl)-3-((4-Hydroxy-2-Methyl-5-Pyrimidinyl)Methyl)-4-Methyl-Thi ; Azolium
MF: C12H17Cl2N3O2S
MW: 338.25
Storage temp.: −20°C
Following is the molecular structure of Oxythiamine (CAS NO.136-16-3) is:

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 1430mg/kg (1430mg/kg)   Pharmaceutical Chemistry Journal Vol. 16, Pg. 848, 1982.

Safety Profile

Moderately toxic by subcutaneous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.

Specification

Oxythiamine (CAS NO.136-16-3) differs from thiamine in having the amino group in the pyrimidine ring replaced by a hydroxyl group and that is a thiamine antagonist producing symptoms of thiamine deficiency.