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CAS No.: | 13993-65-2 |
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Name: | metiazinic acid |
Article Data: | 12 |
Molecular Structure: | |
Formula: | C15H13 N O2 S |
Molecular Weight: | 271.34 |
Synonyms: | Phenothiazine-2-aceticacid, 10-methyl- (8CI); (10-Methyl-2-phenothiazinyl)acetic acid; BAY 4512;Metazionic acid; Methiazic acid; Methiazinic acid; Metiazic acid; Metiazinicacid; RP 16091; Soridermal; Soripal |
Density: | 1.329g/cm3 |
Melting Point: | 146° |
Boiling Point: | 482.6°C at 760 mmHg |
Flash Point: | 245.7°C |
Solubility: | 31mg/L(30 oC) |
Safety: | Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. An experimental teratogen. Experimental reproductive effects. An anti-inflammatory agent. When heated to decomposition it emits very toxic fumes of SOx and NOx. |
PSA: | 65.84000 |
LogP: | 3.61120 |
1. | orl-rat LD50:495 mg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),822. | ||
2. | ipr-rat LD50:365 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 9 (1975),429. | ||
3. | scu-rat LD50:405 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),107. | ||
4. | orl-mus LD50:800 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 19 (1969),1198. | ||
5. | ipr-mus LD50:350 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 9 (1975),429. | ||
6. | scu-mus LD50:490 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 19 (1969),1207. | ||
7. | ivn-mus LD50:350 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 19 (1969),1198. | ||
8. | orl-dog LD50:2000 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 19 (1969),1207. | ||
9. | orl-gpg LD50:225 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 19 (1969),1207. |