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CAS No.: | 141-66-2 |
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Name: | DICROTOPHOS |
Molecular Structure: | |
Formula: | C8H16 N O5 P |
Molecular Weight: | 237.22 |
Synonyms: | Phosphoricacid, (1E)-3-(dimethylamino)-1-methyl-3-oxo-1-propenyl dimethyl ester (9CI);Phosphoric acid, 3-(dimethylamino)-1-methyl-3-oxo-1-propenyl dimethyl ester,(E)-; Phosphoric acid, dimethyl ester, ester with3-hydroxy-N,N-dimethylcrotonamide, (E)- (8CI);3-(Dimethoxyphosphinyloxy)-N,N-dimethyl-cis-crotonamide; 3-Hydroxy-N,N-dimethyl-cis-crotonamidedimethyl phosphate; Bidrin; C 709; Carbicron; Carbomicron; Dicrotophos;Dimethyl 1-dimethylcarbamoyl-1-propen-2-yl phosphate; Dimethyl2-dimethylcarbamoyl-1-methylvinyl phosphate; ENT 24,482; Ektafos; Karbicron;Oleobidrin; SD 3562; trans-Bidrin |
EINECS: | 205-494-3 |
Density: | 1.176g/cm3 |
Melting Point: | <25℃ |
Boiling Point: | 307.5°Cat760mmHg |
Flash Point: | 100℃ |
Solubility: | Totally miscible |
Hazard Symbols: | Cholinesterase inhibitor. TLV: 0.25 mg/m3. Toxic by skin absorption. |
Risk Codes: | 24-28-50/53 |
Safety: | Poison by ingestion, inhalation, skin contact, subcutaneous, intravenous, and intraperitoneal routes. Mutation data reported. Used to control the coffee borer and certain economically important pests of cotton. When heated to decomposition it emits very toxic fumes of NOx and POx. See also ESTERS. |
PSA: | 74.88000 |
LogP: | 1.39590 |
Empirical Formula: C8H16NO5P
Molecular Weight: 237.1901 g/mol
EINECS: 205-494-3
Index of Refraction: 1.456
Density: 1.176 g/cm3
Flash Point: 139.7 °C
Enthalpy of Vaporization: 54.81 kJ/mol
Boiling Point: 307.5 °C at 760 mmHg
Vapour Pressure: 0.000724 mmHg at 25 °C
Solubility: Water soluble
Appearance: A yellow to brown liquid with a mild ester odor
Structure of Dicrotophos (CAS NO.141-66-2):
Product Categories of Dicrotophos (CAS NO.141-66-2): Pesticides & Metabolites;Alphabetic;Insecticides;Organophorous
IUPAC Name: [(E)-4-(Dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate
Canonical SMILES: CC(=CC(=O)N(C)C)OP(=O)(OC)OC
Isomeric SMILES: C/C(=C\C(=O)N(C)C)/OP(=O)(OC)OC
InChI: InChI=1S/C8H16NO5P/c1-7(6-8(10)9(2)3)14-15(11,12-4)13-5/h6H,1-5H3/b7-6+
InChIKey: VEENJGZXVHKXNB-VOTSOKGWSA-N
Dicrotophos (CAS NO.141-66-2) can be used to control sucking, boring, and chewing pests on rice, cotton, coffee, apples, and other crops. It is effective on ornamentals, trees, and shrubs for aphids, leaf hoppers, and scale insects.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
bird - wild | LD50 | oral | 1mg/kg (1mg/kg) | ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979. | |
bird - wild | LD50 | skin | 1300ug/kg (1.3mg/kg) | Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973. | |
chicken | LD50 | oral | 7970ug/kg (7.97mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Toxicology and Applied Pharmacology. Vol. 7, Pg. 606, 1965. |
duck | LD50 | oral | 4140ug/kg (4.14mg/kg) | Toxicology and Applied Pharmacology. Vol. 22, Pg. 556, 1972. | |
mouse | LD50 | intraperitoneal | 9500ug/kg (9.5mg/kg) | Toxicology and Applied Pharmacology. Vol. 16, Pg. 446, 1970. | |
mouse | LD50 | intravenous | 9900ug/kg (9.9mg/kg) | Journal of Pharmacy and Pharmacology. Vol. 19, Pg. 612, 1967. | |
mouse | LD50 | oral | 11mg/kg (11mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 196, 1973. | |
mouse | LD50 | subcutaneous | 11500ug/kg (11.5mg/kg) | Journal of Pharmacy and Pharmacology. Vol. 19, Pg. 612, 1967. | |
pigeon | LD50 | oral | 2mg/kg (2mg/kg) | Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971. | |
quail | LD50 | oral | 4mg/kg (4mg/kg) | Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971. | |
rabbit | LD50 | skin | 168mg/kg (168mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 196, 1973. | |
rat | LC50 | inhalation | 90mg/m3/4H (90mg/m3) | Proceedings of the European Society for the Study of Drug Toxicity. Vol. 15, Pg. 239, 1974. | |
rat | LD50 | oral | 13mg/kg (13mg/kg) | Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 6, 1966. | |
rat | LD50 | skin | 42mg/kg (42mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
rat | LD50 | subcutaneous | 8137ug/kg (8.137mg/kg) | British Journal of Pharmacology. Vol. 40, Pg. 124, 1970. | |
rat | LD50 | unreported | 22mg/kg (22mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 314, 1971. |
EPA Farm Worker Reentry (39 FR 16888,74). EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List.
Poison by ingestion, inhalation, skin contact, subcutaneous, intravenous, and intraperitoneal routes. Mutation data reported. Used to control the COFFEE borer and certain economically important pests of cotton. When heated to decomposition it emits very toxic fumes of NOx and POx. See also ESTERS.
Hazard Codes: NT+
Risk Statements: 24-28-50/53
R24:Toxic in contact with skin.
R28:Very toxic if swallowed.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 28-36/37-45-60-61
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
OSHA PEL: TWA 0.25 mg/m3 (skin)
ACGIH TLV: TWA 0.05 mg/m3 (skin); Not Classifiable as a Human Carcinogen
Dicrotophos ,its cas register number is 141-66-2. It also can be called Bidirl ; O,O-Dimethyl 1-(N,N-dimethylcarbamoyl)-1-propen-2-yl phosphate ; Dimethyl 2-Dimethylcarbamoyl-1-methylvinyl Phosphate ;and (E)-3-(Dimethylamino)-1-methyl-3-oxoprop-1-enyl dimethyl phosphate . It is susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. Dicrotophos (CAS NO.141-66-2) is incompatible with the following: Metals .