CAS No.1435-55-8,HYDROQUINIDINE Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	1435-55-8
Name:	HYDROQUINIDINE
Article Data:	31

Formula:	C₂₀H₂₆N₂O₂
Molecular Weight:	326.439
Synonyms:	Hydroquinidine(6CI,7CI,8CI);(+)-Hydroquinidine;(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol;10,11-Dihydroquinidine;Dihydroquinidine;
EINECS:	215-862-5
Density:	1.204 g/cm³
Melting Point:	169-170 °C(lit.)
Boiling Point:	498.365 °C at 760 mmHg
Flash Point:	255.202 °C
Solubility:	chloroform: 0.1 g/mL, clear
Hazard Symbols:	Xn
Risk Codes:	20/21/22
Safety:	36/37-36
Transport Information:	UN 1544
PSA:	45.59000
LogP:	3.33510

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Chemistry

IUPAC Name: (S)-[(5R,7R)-5-Ethyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)
methanol
Product Name: Hydroquinidine
The MF of Hydroquinidine (CAS NO.1435-55-8) is C₂₀H₂₆N₂O₂.

The MW of Hydroquinidine (CAS NO.1435-55-8) is 326.43.
Synonyms of Hydroquinidine (CAS NO.1435-55-8): (9s)-10,11-Dihydro-6’-methoxycinchonan-9-ol ; (9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol ; 10,11-Dihydroquinidine ; 11-Dihydro-6’-methoxy-1(9s)-cinchonan-9-O ; 6'-Methoxy-10,11-dihydrocinchonan-9-ol ; Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)- ; Hydroconchinine
Index of Refraction: 1.626
EINECS: 215-862-5
Density: 1.2 g/ml
Flash Point: 255.2 °C
Boiling Point: 498.4 °C

Production

preparation products: hydroquinine (anthraquinone-1 4-diyl)-->hydroquinidine (anthraquinone-1,4-diyl) diether-->(dhqd)2pyr-->(dhqd)2phal

Toxicity Data With Reference

1.	orl-rat LD50:369 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 27 (1977),589.
2.	ivn-rat LD50:32 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 27 (1977),589.
3.	ivn-mus LD50:56,500 µg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 84 (1945),184.

Safety Profile

A poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.Safety information of Hydroquinidine (CAS NO.1435-55-8):
Hazard Codes Harmful Xn
Risk Statements
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
Safety Statements
36/37 Wear suitable protective clothing and gloves
RIDADR 1544
WGK Germany 3
RTECS MX3016000
HazardClass 6.1(b)
PackingGroup III