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Basic Information
CAS No.: 1456-28-6
Name: N-nitroso-2,6-dimethylmorpholine
Molecular Structure:
Molecular Structure of 1456-28-6 (N-nitroso-2,6-dimethylmorpholine)
Formula: C6H12 N2 O2
Molecular Weight: 144.173
Synonyms: 2,6-Dimethyl-N-nitrosomorpholine;2,6-Dimethylnitrosomorpholine; N-Nitroso-2,6-dimethylmorpholine; NSC 69924
Density: 1.22g/cm3
Boiling Point: 231.7°C at 760 mmHg
Flash Point: 93.9°C
Solubility: 124g/L(24 oC)
Safety: Suspected carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Poison by ingestion and subcutaneous routes. Mutation data reported. Used as a model carcinogenic and carcinogenic metabolite. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
PSA: 41.90000
LogP: 0.71490
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Chemistry

Empirical Formula: C6H12N2O2
Molecular Weight: 144.1717 g/mol
Index of Refraction: 1.531
Density: 1.22 g/cm3
Flash Point: 93.9 °C
Enthalpy of Vaporization: 44.93 kJ/mol
Boiling Point: 231.7 °C at 760 mmHg
Vapour Pressure: 0.0933 mmHg at 25 °C
Structure of N-Nitroso-2,6-dimethylmorpholine (CAS NO.1456-28-6):
              
IUPAC Name of N-Nitroso-2,6-dimethylmorpholine (CAS NO.1456-28-6): 2,6-Dimethyl-4-nitrosomorpholine

Toxicity Data With Reference

1.    

mmo-sat 1 mg/plate

    TCMUD8    Teratogenesis, Carcinogenesis, and Mutagenesis. 1 (1980),295.
2.    

mma-sat 50 nmol/plate

    MUREAV    Mutation Research. 57 (1978),1.
3.    

dns-rat:lvr 1 mmol/L

    MUREAV    Mutation Research. 144 (1985),197.
4.    

scu-rat LD50:387 mg/kg

    CALEDQ    Cancer Letters (Shannon, Ireland). 13 (1981),159.
5.    

orl-gpg LD50:280 mg/kg

    JJIND8    JNCI, Journal of the National Cancer Institute. 64 (1980),529.
6.    

orl-ham LD50:367 mg/kg

    JNCIAM    Journal of the National Cancer Institute. 58 (1977),429.
7.    

scu-ham LD50:320 mg/kg

    JNCIAM    Journal of the National Cancer Institute. 60 (1978),197.

Consensus Reports

EPA Genetic Toxicology Program.

Safety Profile

Suspected carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Poison by ingestion and subcutaneous routes. Mutation data reported. Used as a model carcinogenic and carcinogenic metabolite. When heated to decomposition N-Nitroso-2,6-dimethylmorpholine (CAS NO.1456-28-6) emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.

Specification

 N-Nitroso-2,6-dimethylmorpholine ,its cas register number is 1456-28-6. It also can be called Morpholine, 2,6-dimethyl-4-nitroso-, (E)- ; Morpholine, 2,6-dimethyl-4-nitroso-, (Z)- ; and Morpholine, 2,6-dimethyl-4-nitroso- .