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Basic Information
| CAS No.: | 14901-08-7 |
|---|---|
| Name: | Cycasin |
| Molecular Structure: | |
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| Formula: | C8H16 N2 O7 |
| Molecular Weight: | 252.224 |
| Synonyms: | Cycasin(6CI,7CI,8CI); b-D-Glucopyranoside,[(Z)-methyl-ONN-azoxy]methyl (9CI); Methylazoxymethanol glucoside;Methylazoxymethanol b-D-glucoside; NSC 15190 |
| Density: | 1.71g/cm3 |
| Melting Point: | 154°C (rough estimate) |
| Boiling Point: | 479.5°Cat760mmHg |
| Flash Point: | 243.8°C |
| Safety: | Confirmed carcinogen with experimental carcinogenic and tumorigenic data. A poison by ingestion. An experimental teratogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. |
| PSA: | 140.49000 |
| LogP: | -2.12410 |
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Cycasin
Chemistry
Molecular formula: C8H16N2O7
Drugs known as cycads glycosides. NEEDLE crystallization (water + + ether acetone). Decomposition point 154 ° C, -44 ° degree rotation (c = 0.62). Cycads existed in the natural plant cycads (Cycasrevoluta Thunb.) The leaves, cones, seeds and other plants.
Toxicity Data With Reference
CYCASIN is carcinogenic, to oral feeding rats can produce liver and kidney, its main ingredients are carcinogenic poison DAIDZEIN cycads. However, the subcutaneous injection of goods and another anti-mouse Ehrlich ascites carcinoma and this effect with mitomycin C, similar to oxygen nitrogen mustard. With the performance of the administration of the dual nature of both carcinogenic effect has anti-tumor effects. The pair of cold-blooded goods toxicity. The mice did not have to immediately poisoning, but by 12 ~ 18 h then see dyspnea, respiratory paralysis finally died.