Products Categories
| CAS No.: | 152-11-4 |
|---|---|
| Name: | (+/-)-Verapamil hydrochloride |
| Molecular Structure: | |
|
|
|
| Formula: | C27H38N2O4.HCl |
| Molecular Weight: | 491.071 |
| Synonyms: | Benzeneacetonitrile,a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-,monohydrochloride (9CI);Valeronitrile, 5-[(3,4-dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-,monohydrochloride (8CI);Akilen;Anpec;Apoacor;Arapamyl;Berkatens;Calan SR;Calaptin 240SR;Calaptin 80;Cardiabeltin;Civicor Retard;Cordilox;Dignover;Dilacoran HTA;Finoptin; |
| EINECS: | 205-800-5 |
| Density: | 1.058g/cm3 |
| Melting Point: | 142 °C (dec.)(lit.) |
| Boiling Point: | 586.1 °C at 760 mmHg |
| Flash Point: | 308.3 °C |
| Solubility: | water: >30 mg/mL |
| Appearance: | white to off-white powder |
| Hazard Symbols: |
 T
|
| Risk Codes: | 25-23/24/25 |
| Safety: | 45-36/37/39-36/37 |
| Transport Information: | UN 2811 6.1/PG 3 |
| PSA: | 63.95000 |
| LogP: | 5.89508 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 211914-50-0N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride
- 144689-24-71H-Imidazole-5-carboxylicacid,4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
- 13292-87-0Boron,trihydro[thiobis[methane]]-, (T-4)-
- 10294-26-5Sulfuric acid,silver(1+) salt (1:2)
- 106-22-96-Octen-1-ol,3,7-dimethyl-
- 121-03-9Benzenesulfonic acid,2-methyl-5-nitro-
- 105-55-5N,N'-Diethylthiourea
- 985-12-6Isoquinoline,1-[(3,4-diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydro-,hydrochloride (1:1)
- 10450-60-9Periodic acid
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Chemistry
Product Name: Verapamil hydrochloride (CAS NO.152-11-4)
IUPAC Name: 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile hydrochloride
Molecular Formula: C27H39ClN2O4
Molecular Weight: 491.062560 g/mol
Appearance: odorless white solid
Melting Point: 142 °C (dec.)(lit.)
Boiling Point: 586.1 °C at 760 mmHg
Flash Point: 308.3 °C
Water solubility: >30 mg/mL
Merck: 13,10012
EINECS: 205-800-5
Product Categories: Miscellaneous Biochemicals; Organics; Calcium channel
Uses
Verapamil hydrochloride (CAS NO.152-11-4) is primarily for the treatment of paroxysmal supraventricular tachycardia, also used the treatment of angina, hypertension, and hypertrophic cardiomyopathy infarction.
Toxicity Data With Reference
| 1. | cyt-hmn:lyms 30 µmol/L | MUREAV Mutation Research. 244 (1990),135. | ||
| 2. | orl-man TDLo:26 mg/kg:CVS,PUL | HUTODJ Human Toxicology. 4 (1985),327. | ||
| 3. | orl-man TDLo:143 µg/kg/4H-C:CVS | ICMED9 Intensive Care Medicine. 8 (1982),55. | ||
| 4. | ivn-man LDLo:256 µg/kg/1H-I:CVS | AEMED3 Annals of Emergency Medicine. 14 (1985),159. | ||
| 5. | ivn-man TDLo:71 µg/kg/5M-C | SMJOAV Southern Medical Journal. 75 (1982),1429. | ||
| 6. | orl-wmn TDLo:135 mg/kg:EYE,PUL | AJCDAG American Journal of Cardiology. 58 (1986),1142. | ||
| 7. | ivn-wmn TDLo:200 µg/kg/15S-C:CVS,PUL | NYSJAM New York State Journal of Medicine. 83 (1983),1181. | ||
| 8. | orl-inf TDLo:80 mg/kg | PEDIAU Pediatrics. 73 (1984),543. | ||
| 9. | ivn-inf TDLo:1026 µg/kg:CVS | ADCHAK Archives of Disease in Childhood. 58 (1983),465. | ||
| 10. | orl-rat LD50:108 mg/kg | NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),766. | ||
Safety Profile
Safety Information of Verapamil hydrochloride (CAS NO.152-11-4):
Hazard Codes:T 
Risk Statements:25-23/24/25
Safety Statements:45-36/37/39-36/37
RIDADR:UN 2811 6.1/PG 3
WGK Germany:3
RTECS:YV8320000
F:8-10
HazardClass:6.1(b)
PackingGroup:III
Poison by ingestion, subcutaneous, intramuscular, intravenous, and intraperitoneal routes. Human systemic effects; arrhythmias, cardiomyopathy, coma, cyanosis, dyspnea, fall in blood pressure, mydriasis, pulse rate decrease. Human reproductive effects: impotence. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl.
Specification
Verapamil hydrochloride , its CAS NO. is 152-11-4, the synonyms are (+/-)-Verapamil hydrochloride ; 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-valeronitril ; Cordilox ; Finoptin ; Iproveratrilhydrochloride ; Izoptinhydrochloride .