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15922-78-8

Basic Information
CAS No.: 15922-78-8
Name: pyrithione sodium
Molecular Structure:
Molecular Structure of 15922-78-8 (pyrithione sodium)
Formula: C5H5NOS.Na
Molecular Weight: 150.16
Synonyms: 1-Hydroxypyridine-2-thione sodium salt;2(1H)-Pyridinethione, 1-hydroxy-, sodium salt(8CI,9CI);AL 02725;N-Hydroxy-2(1H)-pyridinethione sodium salt;N-Hydroxy-2-thiopyridone sodiumsalt;N-Hydroxypyridine-2-thione sodium salt;Omacide 24;Pyrithione sodium;Sodium 1-hydroxy-2(1H)-pyridinethionate;Sodium pyridinethione;2(1H)-Pyridinethione,1-hydroxy-, sodium deriv. (6CI);
EINECS: 240-062-8
Density: g/cm3
Boiling Point: 253.8°Cat760mmHg
Flash Point: 107.3°C
Safety: Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of Na2O, NOx, and SOx.
PSA: 45.23000
LogP: 2.12160
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Chemistry

IUPAC Name: 1-Hydroxy-2(1H)-pyridinethione Sodium Salt
The MF of 1-Hydroxy-2(1H)-pyridinethione Sodium Salt (15922-78-8) is C5H4NNaOS.
                                        
The MW of 1-Hydroxy-2(1H)-pyridinethione Sodium Salt (15922-78-8) is 149.1461.
Synonyms of 1-Hydroxy-2(1H)-pyridinethione Sodium Salt (15922-78-8): 2(1H)-Pyridinethione, 1-hydroxy-, sodium salt (1:1) ; Sodium 2-thioxo-1(2H)-pyridinolate ; Sodium omadine (VAN) ; (1-Hydroxy-2-pyridinethione), sodium salt
Flash Point: 107.3 °C
Boiling Point: 253.8 °C 
EINECS: 240-062-8

Uses

  1-Hydroxy-2(1H)-pyridinethione Sodium Salt (15922-78-8) is used as pharmaceutical intermediate.

Toxicity Data With Reference

1.    

orl-rat LDLo:745 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),156.
2.    

ipr-rat LDLo:385 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),156.
3.    

orl-mus LD50:870 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 8 (1974),1067.
4.    

ipr-mus LD50:265 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),156.
5.    

scu-mus LD50:428 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 8 (1984),1067.
6.    

ivn-mus LD50:335 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),156.
7.    

ivn-rbt LDLo:200 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 9 (1966),269.

Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of Na2O, NOx, and SOx.

Standards and Recommendations

DFG MAK: 1 mg/m3