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18760-80-0

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Basic Information
CAS No.: 18760-80-0
Name: DL-Methylephedrine hydrochloride
Article Data: 1
Molecular Structure:
Molecular Structure of 18760-80-0 (DL-Methylephedrine hydrochloride)
Formula: C11H17 N O . Cl H
Molecular Weight: 215.723
Synonyms: Benzenemethanol,a-[(1R)-1-(dimethylamino)ethyl]-,hydrochloride, (aS)-rel-(9CI); Benzenemethanol, a-[1-(dimethylamino)ethyl]-, hydrochloride, (R*,S*)-(?à)-; Benzyl alcohol, a-[1-(dimethylamino)ethyl]-,hydrochloride, erythro-(?à)- (8CI); (?à)-N-Methylephedrinehydrochloride; Benzenemethanol, a-[1-(dimethylamino)ethyl]-, hydrochloride, (R*,S*)-; dl-Methylephedrinehydrochloride
EINECS: 242-557-4
Density: g/cm3
Boiling Point: 251.3°Cat760mmHg
Flash Point: 96.9°C
Safety: Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx and HCl.
PSA: 23.47000
LogP: 2.47210
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Chemistry

Chemical Name: dl-Methylephedrine hydrochloride
IUPAC NAME: 2-(Dimethylamino)-1-phenylpropan-1-ol hydrochloride
CAS No.: 18760-80-0
EINECS: 242-557-4
Molecular Formula: C11H18ClNO
Molecular Weight: 215.72 g/mol
Flash Point: 96.9 °C
Boiling Point: 251.3 °C at 760 mmHg
Following is the structure of dl-N-Methylphedrine hydrochloride (18760-80-0):


The chemical synonymous of dl-N-Methylphedrine hydrochloride (18760-80-0) are dl-Methylephedrine hydrochloride ; (R*,S*)-(±)-alpha-[1-(Dimethylamino)ethyl]benzyl alcohol hydrochloride ; dl-Methylephedrine HCl ; Metheph ; Benzenemethanol, α-[(1R)-1-(dimethylamino)ethyl]-, hydrochloride, (αS)-rel- ; Benzenemethanol, α-[1-(dimethylamino)ethyl]-, hydrochloride, (R*,S*)- ; Benzenemethanol, α-[1-(dimethylamino)ethyl]-, hydrochloride, (R*,S*)-(+-)- ; Benzyl alcohol, α-[1-(dimethylamino)ethyl]-, hydrochloride, erythro-(+-)- (8CI)

Toxicity Data With Reference

1.    

orl-mus LD50:758 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),827.
2.    

scu-mus LD50:484 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),827.
3.    

ivn-mus LD50:134 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),827.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx and HCl.