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21848-62-4

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Basic Information
CAS No.: 21848-62-4
Name: [6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-4H-dibenzo[de,g]quinoline
Article Data: 6
Molecular Structure:
Molecular Structure of 21848-62-4 ([6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-4H-dibenzo[de,g]quinoline)
Formula: C20H23NO4
Molecular Weight: 341.407
Synonyms: O,O-Dimethyllaurelliptine;(+)-N-Norglaucine;Norglaucin;d-N-Norglaucine;1,2,9,10-tetramethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline;N-demethyl glaucine;Laurelliptine,O,O'-dimethyl;(+)-norglausine;4H-Dibenzo(de,g)quinoline,5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-,(S);(-)-norglaucine;
Density: 1.178g/cm3
Boiling Point: 501.2°C at 760 mmHg
Flash Point: 208.5°C
Safety: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
PSA: 48.95000
LogP: 3.45970
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Chemistry

Product Name: Norglaucine 
Synonyms of Norglaucine (CAS NO.21848-62-4) : (+)-N-Norglaucine ; 1,2,9,10-Tetramethoxy-6a-alpha-noraporphine ; 4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-, (S)- ; 6a-alpha-Noraporphine, 1,2,9,10-tetramethoxy- ; Laurelliptine, O,O'-dimethyl- (7CI) ; Norglaucine ; O,O-Dimethyllaurelliptine
InChI: InChI=1/C20H23NO4/c1-22-15-9-12-7-14-18-11(5-6-21-14)8-17(24-3)20(25-4)19(18)13(12)10-16(15)23-2/h8-10,14,21H,5-7H2,1-4H3/t14-/m0/s1 
CAS NO: 21848-62-4   
Molecular Formula:C20H23NO4                             
Molecular Weight :341.4009                                      
Molecular Structure :
Index of Refraction: 1.575  
Surface Tension: 41.1 dyne/cm 
Density: 1.178 g/cm3 
Flash Point: 208.5 °C 
Enthalpy of Vaporization: 77 kJ/mol 
Boiling Point: 501.2 °C at 760 mmHg 
Vapour Pressure: 3.53E-10 mmHg at 25°C 

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 170mg/kg (170mg/kg) CARDIAC: CHANGE IN RATE

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Annales Pharmaceutiques Francaises. Vol. 38, Pg. 537, 1980.
mouse LD50 intravenous 90mg/kg (90mg/kg) CARDIAC: CHANGE IN RATE

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Annales Pharmaceutiques Francaises. Vol. 38, Pg. 537, 1980.
mouse LD50 oral 450mg/kg (450mg/kg) CARDIAC: CHANGE IN RATE

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Annales Pharmaceutiques Francaises. Vol. 38, Pg. 537, 1980.

Safety Profile

Poison by intravenous and intraperitoneal routes. Norglaucine (CAS NO.21848-62-4) is moderately toxic by ingestion. When Norglaucine (CAS NO.21848-62-4) is heated to decomposition ,it emits toxic fumes of NOx.