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23210-58-4

Basic Information
CAS No.: 23210-58-4
Name: IFENPRODIL HEMITARTRATE
Molecular Structure:
Molecular Structure of 23210-58-4 (IFENPRODIL HEMITARTRATE)
Formula: 2(C21H27NO2).C4H6O6
Molecular Weight: 801.08
Synonyms: 4-Benzyl-1-[beta,4-dihydroxy-alpha-methylphenethyl]piperidinium hydrogen tartrate (2:1)
EINECS: 245-493-5
Density: g/cm3
Melting Point: 178-180°C
Boiling Point: 493.5°Cat760mmHg
Flash Point: 248.7°C
Hazard Symbols:
Risk Codes: R20/21/22;R36/37/38   
Safety: Poison by ingestion, intramuscular, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
PSA: 158.76000
LogP: 1.58410
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    IFENPRODIL HEMITARTRATE Basic information Product Name: IFENPRODIL HEMITARTRATE Synonyms: IFENPRODIL TARTRATE;IFENPRODIL TARTRATE SALT;IFENPRODIL HEMITARTRATE;ALPHA-[4-HYDROXYPHENYL]-BETA-METHYL-4-BENZYL-

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Chemistry

IUPAC Name: 4-[2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl]phenol;2,3-Dihydroxybutanedioic acid
Product Name: Ifenprodil hemitartrate
The MF of Ifenprodil hemitartrate (CAS NO.23210-58-4) is C25H33NO8.

               
The MW of Ifenprodil hemitartrate (CAS NO.23210-58-4) is 475.53.
Synonyms of Ifenprodil hemitartrate (CAS NO.23210-58-4): 4-Benzyl-1-[beta,4-dihydroxy-alpha-methylphenethyl]piperidinium hydrogen tartrate ; 2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemitartrate ; Ifenprodil tartarate ; α-(4-Hydroxyphenyl)-β-methyl-4-benzyl-1-piperidineethanol tartrate salt
Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Apperance: Crystalline Solid
Flash Point: 381 °C
Boiling Point: 706.3 °C
Melting Point: 178-180 °C
EINECS: 245-493-5

Uses

   Ifenprodil hemitartrate (CAS NO.23210-58-4) is used as vasodilator (cerebral and peripheral).

Toxicity Data With Reference

1.    

orl-rat LD50:538 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 10 (1975),785.
2.    

ipr-rat LD50:138 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 10 (1975),785.
3.    

ivn-rat LD50:50 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),79.
4.    

ims-rat LD50:240 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 10 (1975),785.
5.    

orl-mus LD50:17 mg/kg

    USXXAM    United States Patent Document. (Commissioner of Patents and Trademarks, Washington, DC 20231) #3509164 .
6.    

ipr-mus LD50:120 mg/kg

    USXXAM    United States Patent Document. (Commissioner of Patents and Trademarks, Washington, DC 20231) #3509164 .
7.    

ivn-mus LD50:44 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 10 (1975),785.
8.    

ims-mus LD50:222 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 10 (1975),785.
9.    

orl-dog LD50:461 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 14 (1977),415.
10.    

ivn-dog LD50:34,200 µg/kg

    OYYAA2    Oyo Yakuri. P

Safety Profile

Poison by ingestion, intramuscular, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.Safety information of Ifenprodil hemitartrate (CAS NO.23210-58-4):
Hazard Codes  HarmfulXn
Risk Statements 
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements 
22 Do not breathe dust
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37 Wear suitable protective clothing and gloves
WGK Germany  3