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24853-80-3

Basic Information
CAS No.: 24853-80-3
Name: Azaphen hydrochloride
Molecular Structure:
Molecular Structure of 24853-80-3 (Azaphen hydrochloride)
Formula: C16H19N5O.2HCl
Molecular Weight: 370.28
Synonyms: 5H-Pyridazino[3,4-b][1,4]benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-, dihydrochloride (8CI,9CI);2-(4-Methylpiperazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride;2-(4-Methylpipirazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride;Azafen;Azaphen;
Boiling Point: 536 °C at 760 mmHg
Flash Point: 278 °C
PSA: 44.73000
LogP: 3.77390
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Chemistry

Chemical Name: Azaphen hydrochloride
IUPAC NAME: 5-Methyl-3-(4-methylpiperazin-1-yl)pyridazino[3,4-b][1,4]benzoxazine dihydrochloride
CAS No.: 24853-80-3
Molecular Formula: C11H8N2O
Molecular Weight: 184.19 g/mol
Flash Point: 278 °C
Boiling Point: 536 °C at 760 mmHg
Following is the structure of Azephen (CAS No.24853-80-3):


The chemical synonymous of Azephen (CAS No.24853-80-3) are Azaphenonxazine ; Azaphen ; 2-(4-Methyl-1-Piperazinyl)-10-Methyl-3,4-Diazphenoxazine Dihydrochloride ; Azaphen Hydrochloride ; Azaphenonxazine 2HCL ; 2-(4-Methyl-1-Piperazinyl)-10-Methyl-3,4-Diazaphenoxazine Dihydrochloride

Toxicity Data With Reference

1.    

orl-rat LD50:1 g/kg

    ZPPLBF    Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787.
2.    

scu-rat LD50:490 mg/kg

    ZPPLBF    Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787.
3.    

ivn-rat LD50:48 mg/kg

    ZPPLBF    Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787.
4.    

orl-mus LD50:700 mg/kg

    PCJOAU    Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 4 (1970),118.
5.    

scu-mus LD50:330 mg/kg

    ZPPLBF    Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787.
6.    

ivn-mus LD50:63 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 37 (1974),2.
7.    

orl-cat LD50:200 mg/kg

    ZPPLBF    Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787.

Safety Profile

Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. An antidepressant.