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27262-48-2

Basic Information
CAS No.: 27262-48-2
Name: Levobupivacaine hydrochloride
Molecular Structure:
Molecular Structure of 27262-48-2 (Levobupivacaine hydrochloride)
Formula: C18H29ClN2O
Molecular Weight: 324.89
Synonyms: 2-Piperidinecarboxamide,1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride, (2S)- (9CI);2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride,(S)-;2',6'-Pipecoloxylidide, 1-butyl-, monohydrochloride, (-)- (8CI);(-)-Bupivacaine monohydrochloride;(S)-(-)-Bupivacaine monohydrochloride;Chirocaine;Popscaine;Levobupivacaine HCL;
EINECS: 1308068-626-2
Density:
Melting Point: 254 °C (dec.)(lit.)
Boiling Point: 423.4 °C at 760 mmHg
Flash Point: 209.9 °C
Solubility:
Appearance: white crystalline powder
Hazard Symbols: VeryT+, HarmfulXn
Risk Codes: 26/27/28-20/21/22-28
Safety: 22-36/37/39-45-36/37-53
Transport Information: UN 2811 6.1/PG 2
PSA: 23.55000
LogP: 4.74080
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    CAS 27262-48-2 Molecular formula C18H29ClN2O Molecular Weight

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    name: levobupivacaine hydrochloride cas no.: 27262-48-2 formula: c18h29cln2o molecular weight: 324.89 synonyms: 2-piperidinecarboxamide,1-butyl-n-(2,6-dimethylphenyl)-, monohydrochloride, (2s)- (9ci);2-piperidinecarboxamide, 1-butyl-n-(2,6-di

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Chemistry

Molecular structure of Levobupivacaine hydrochloride (CAS NO.27262-48-2) is:

Product Name: Levobupivacaine hydrochloride
CAS Registry Number: 27262-48-2
IUPAC Name: (2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride
Molecular Weight: 324.88866 [g/mol]
Molecular Formula: C18H29ClN2O
H-Bond Donor: 2
H-Bond Acceptor: 2
Melting Point: 254 °C (dec.)(lit.)
Flash Point: 209.9 °C
Enthalpy of Vaporization: 67.78 kJ/mol
Boiling Point: 423.4 °C at 760 mmHg
 Vapour Pressure: 2.24E-07 mmHg at 25°C
 Product Categories: Pharmaceutical Raw Materials;Active Pharmaceutical Ingredients

Uses

 Levobupivacaine hydrochloride (CAS NO.27262-48-2) can be used in pain relief.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LD50 intravenous 5100ug/kg (5.1mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.
rabbit LD50 oral 18mg/kg (18mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.
rabbit LD50 parenteral 207mg/kg (207mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.
rat LD50 subcutaneous 63mg/kg (63mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.

Safety Profile

Safty information about Levobupivacaine hydrochloride (CAS NO.27262-48-2) is:
Hazard Codes: VeryT+,HarmfulXn
Risk Statements: 26/27/28-20/21/22-28 
R26/27/28:Very toxic by inhalation, in contact with skin and if swallowed. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R28:Very toxic if swallowed.
Safety Statements: 22-36/37/39-45-36/37-53 
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37:Wear suitable protective clothing and gloves. 
S53:Avoid exposure - obtain special instructions before use.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: TK6125000

Specification

 Levobupivacaine hydrochloride , its cas register number is 27262-48-2. It also can be called Levobupivacaine ; Levobupivacaine hydrochloride [USAN] ; (S)-1-Butyl-2',6'-pipecoloxylidide monohydrochloride ; (S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide monohydrochloride ; Bupicaine hydrochloride (-) ; Chirocaine ; Levobupivacaine HCl ; Levobupivacaine hydrochloride ; 2',6'-Pipecoloxylidide, 1-butyl-, hydrochloride, (-)- ; 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride, (2S)- .It is a white crystalline powder.

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