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304-43-8

Basic Information
CAS No.: 304-43-8
Name: [2S-(2alpha,5alpha,6beta)]-6-[[1,1'-biphenyl]-2-ylformamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Article Data: 2
Molecular Structure:
Molecular Structure of 304-43-8 ([2S-(2alpha,5alpha,6beta)]-6-[[1,1'-biphenyl]-2-ylformamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid)
Formula: C21H20 N2 O4 S
Molecular Weight: 396.467
Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-(2-biphenylcarboxamido)-3,3-dimethyl-7-oxo- (7CI,8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[([1,1'-biphenyl]-2-ylcarbonyl)amino]-3,3-dimethyl-7-oxo-, [2S-(2a,5a,6b)]-; 2-Biphenylpenicillin; Ancillin; Biphenicillin; Diphenicillin;Penicillin, ([1,1'-biphenyl]-2-yl)-; SKF 12141; [2S-(2a,5a,6b)]-6-[[1,1'-Biphenyl]-2-ylformamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid
Density: 1.42g/cm3
Boiling Point: 694.6°Cat760mmHg
Flash Point: 373.9°C
Safety: Moderately toxic by intravenous route. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and SOx. See other penicillin entries.
PSA: 115.50000
LogP: 3.11160
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Toxicity Data With Reference

1.   

orl-mus LD50:5600 mg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 3 (1978),1663.
2.   

ivn-mus LD50:1030 mg/kg

    FATOAO    Farmakologiya i Toksikologiya (Moscow). 31 (1968),232.

Safety Profile

Moderately toxic by intravenous route. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and SOx. See other penicillin entries.