CAS No.306-07-0,PARGYLINE HYDROCHLORIDE Suppliers

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Basic Information

Molecular Structure:
CAS No.:	306-07-0
Name:	PARGYLINE HYDROCHLORIDE

Formula:	C11H13 N . Cl H
Molecular Weight:	195.692
Synonyms:	Benzenemethanamine,N-methyl-N-2-propynyl-, hydrochloride (9CI);Benzylamine, N-methyl-N-2-propynyl-,hydrochloride (6CI,8CI);A 19120;Eutonyl;Eutonyl-ten;MO 911;Methylbenzylpropynylamine hydrochloride;N-Benzyl-N-methyl-2-propynylaminehydrochloride;N-Methyl-N-(2-propynyl)benzylamine hydrochloride;NSC 43798;Pargyline hydrochloride;
EINECS:	206-175-1
Density:	g/cm³
Melting Point:	160-163 ºC(lit.)
Boiling Point:	228.4 ºC at 760 mmHg
Flash Point:	83.9 ºC
Hazard Symbols:	Xn
Risk Codes:	22
Safety:	Poison by ingestion, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: effects on fluid intake, psychological effects. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NO_x.
PSA:	3.24000
LogP:	2.55360

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Chemistry

IUPAC Name: N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride
Synonyms: Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1) ; N-Benzyl-N ; Methylprop-2-yn-1-amine hydrochloride (1:1) ; N-Methyl-N-2-propynylbenzenemethanamine Hydrochloride ; 2-Propynylamine, N-benzyl-N-methyl-, hydrochloride
CAS NO: 306-07-0
Molecular Formula of Benzylmethylpropynylamine hydrochloride (CAS NO.306-07-0) : C₁₁H₁₄ClN
Molecular Weight of Benzylmethylpropynylamine hydrochloride (CAS NO.306-07-0) : 195.69
Molecular Structure of Benzylmethylpropynylamine hydrochloride (CAS NO.306-07-0) :
EINECS: 206-175-1
Merck : 13,7110
Mol File: 306-07-0.mol
Flash Point: 83.9 °C
Enthalpy of Vaporization: 46.5 kJ/mol
Boiling Point: 228.4 °C at 760 mmHg
Vapour Pressure: 0.0736 mmHg at 25°C
Melting point: 160-163 °C(lit.)
Storage temp: -20°C

Uses

Benzylmethylpropynylamine hydrochloride (CAS NO.306-07-0) is a monoamine oxidase inhibitor,which has a clear antihypertensive effect.

Toxicity Data With Reference

1.	orl-man TDLo:108 mg/kg/26W-I	JCLPDE Journal of Clinical Psychiatry. 44 (1983),25.
2.	orl-wmn TDLo:1500 µg/kg/D:CNS,PSY	AJPSAO American Journal of Psychiatry. 118 (1961),255.
3.	orl-rat LD50:250 mg/kg	27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,401.
4.	ipr-rat LD50:142 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 107 (1963),1068.
5.	ivn-rat LD50:175 mg/kg	27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,401.
6.	orl-mus LD50:680 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 107 (1963),1068.
7.	ipr-mus LD50:300 mg/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .
8.	orl-dog LD50:175 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 107 (1963),1068.

Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: effects on fluid intake, psychological effects. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NO_x.Hazard Codes Xn
Risk Statements 22
R22:Harmful if swallowed.
Safety Statements 22-24/25
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS DP6650000
F 10
HazardClass 6.1(b)
PackingGroup III