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311-45-5

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Basic Information
CAS No.: 311-45-5
Name: PARAOXON
Article Data: 59
Molecular Structure:
Molecular Structure of 311-45-5 (PARAOXON)
Formula: C10H14 N O6 P
Molecular Weight: 275.198
Synonyms: Phosphoricacid, diethyl p-nitrophenyl ester (6CI,8CI); 4-Nitrophenyl diethyl phosphate;Chinorto; Diethyl 4-nitrophenyl phosphate; Diethyl p-nitrophenyl phosphate; E600; E 600 (pesticide); Ester 25; Ethyl paraoxon; Eticol; Fosfakol; HC 2072;Mintacol; Miotisal; Miotisal A; NSC 404110; O,O-Diethyl O-p-nitrophenylphosphate; O-(4-Nitrophenyl) O,O-diethyl phosphate; Oxyparathion; Paraoxan;Paraoxon; Paraoxon-ethyl; Phosphachole; Phosphacol; Phosphakol; Ts 219;p-Nitrophenyl diethyl phosphate
Density: 1.3g/cm3
Melting Point: 300°C
Boiling Point: 344.7°Cat760mmHg
Flash Point: 162.3°C
Solubility: 3.627g/L(20 oC)
Hazard Symbols: Poison by ingestion, inhalation, and skin absorption; cholinesterase inhibitor; use may be restricted.
Risk Codes: 26/27/28
Safety: A deadly poison by ingestion, intraperitoneal, intravenous, subcutaneous, intramuscular, and parenteral routes. Mutation data reported. Human systemic effects: coma, convulsions, miosis. A cholinesterase inhibitor. An insecticide. When heated to decomposition it emits toxic fumes of POx and NOx. See also PARATHION.
PSA: 100.39000
LogP: 3.67790
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Chemistry

Molecular Formula: C10H14NO6P
Molecular Weight: 275.2
EINECS: 206-221-0
Density: 1.274 g/mL at 25 °C(lit.) 
Refractive index: n20/D 1.51(lit.)
Storage temp.: 2-8°C 
Color: Yellow
Chemical Properties: Oily Liquid
Paraoxon's(311-45-5) Synonyms: DIETHYL P-NITROPHENYL PHOSPHATE;E 600;ESTER 25;FOSFAKOL;ETICOL;Chinorta;Chinorto;Diaethyl-p-nitrophenylphosphorsaeureester
Paraoxon's(311-45-5) structural formula:

Uses

Paraoxon(311-45-5) is used as a cholinesterase inhibitor.

Toxicity Data With Reference

1.   

mmo-ssp 5 mmol/L

   MUREAV    Mutation Research. 117 (1983),139.
2.   

sce-ham:ovr 100 µmol/L

   JTEHD6    Journal of Toxicology and Environmental Health. 8 (1981),939.
3.   

orl-man TDLo:14 mg/kg:EYE,BAH

   ATXKA8    Archiv fuer Toxikologie. 25 (1969),329.
4.   

orl-rat LD50:1800 µg/kg

   BCPCA6    Biochemical Pharmacology. 16 (1967),1183.
5.   

ipr-rat LD50:716 µg/kg

   PCBPBS    Pesticide Biochemistry and Physiology. 26 (1986),202.
6.   

scu-rat LD50:230 µg/kg

   NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),113.
7.   

ivn-rat LD50:240 µg/kg

   CJBPAZ    Canadian Journal of Biochemistry and Physiology. 34 (1956),197.
8.   

ims-rat LD50:446 µg/kg

   BJIMAG    British Journal of Industrial Medicine. 22 (1965),317.
9.   

orl-mus LD50:760 µg/kg

   HPFSDS    HHS Publication (FDA. United States). (U.S. Government Printing Office, Superintendent of Documents, Washington, DC 20402) 1980- FDA-80-1076,212 ,1980.
10.   

ipr-mus LD50:330 µg/kg

&

Safety Profile

A deadly poison by ingestion, intraperitoneal, intravenous, subcutaneous, intramuscular, and parenteral routes. Mutation data reported. Human systemic effects: coma, convulsions, miosis. A cholinesterase inhibitor. An insecticide. When heated to decomposition it emits toxic fumes of POx and NOx. See also PARATHION.

Safety Information for Paraoxon(311-45-5)
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  36/37/39-45
RIDADR  UN 2810 6.1/PG 1
WGK Germany  3
RTECS  TC2275000
HazardClass  6.1(a)
PackingGroup  I