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334-22-5

Basic Information
CAS No.: 334-22-5
Name: Nornitrogen mustard
Article Data: 31
Molecular Structure:
Molecular Structure of 334-22-5 (Nornitrogen mustard)
Formula: C4H9 Cl2 N
Molecular Weight: 142.028
Synonyms: Diethylamine,2,2'-dichloro- (6CI,8CI); 2,2'-Dichlorodiethylamine; Bis(2-chloroethyl)amine;Bis(b-chloroethyl)amine; Di(2-chloroethyl)amine;N,N-Bis(2-chloroethane)amine; N,N-Bis(2-chloroethyl)amine; N,N-Bis(b-chloroethyl)amine; Nor-HN2;Nor-N-mustard; Nor-mechlorethamine; Nor-mustard; Nor-nitrogen mustard; b,b-Dichlorodiethylamine
Density: 1.125g/cm3
Boiling Point: 204.2°Cat760mmHg
Flash Point: 77.3°C
Safety: Poison by intraperitoneal, subcutaneous, and intravenous routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic NOx and Cl.
PSA: 12.03000
LogP: 1.44450
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Chemistry

Chemistry informtion about Nornitrogen Mustard (CAS NO.334-22-5) is:
IUPAC Name: 2-Chloro-N-(2-Chloroethyl)Ethanamine
Synonyms: Nornitrogen Mustard ; Nor-N-Mustard ; 1,1'-Iminobis(2-Chloroethane) ; 2-Chloro-N-(2-Chloroethyl)Ethanamine ; Nor-Mustard
MF: C4H9Cl2N
MW: 142.026960 g/mol 
Density: 1.125 g/cm3
Flash Point: 77.3 °C
Boiling Point: 204.2 °C at 760 mmHg
Vapour Pressure: 0.267 mmHg at 25°C 
Enthalpy of Vaporization: 44.04 kJ/mol
Following is the molecular structure of Nornitrogen Mustard (CAS NO.334-22-5) is:

Uses

Nornitrogen Mustard (CAS NO.334-22-5) is common used in medicinal.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 5700ug/kg (5.7mg/kg) gastrointestinal: other changes blood: leukopenia blood: other changes Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965.
monkey LDLo intravenous 11mg/kg (11mg/kg)
gastrointestinal: other changes blood: leukopenia blood: other changes
Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965.
mouse LD50 intraperitoneal 142mg/kg (142mg/kg)   Journal of Medicinal Chemistry. Vol. 8, Pg. 167, 1965.
mouse LD50 subcutaneous 20mg/kg (20mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 91, Pg. 224, 1947.
rat LD50 intraperitoneal 97mg/kg (97mg/kg)   Journal of Medicinal Chemistry. Vol. 8, Pg. 167, 1965.
rat LD50 intravenous 100mg/kg (100mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1149, 1974.

Safety Profile

Poison by intraperitoneal, subcutaneous, and intravenous routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic NOx and Cl.