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| CAS No.: | 334-22-5 |
|---|---|
| Name: | Nornitrogen mustard |
| Molecular Structure: | |
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| Formula: | C4H9 Cl2 N |
| Molecular Weight: | 142.028 |
| Synonyms: | Diethylamine,2,2'-dichloro- (6CI,8CI); 2,2'-Dichlorodiethylamine; Bis(2-chloroethyl)amine;Bis(b-chloroethyl)amine; Di(2-chloroethyl)amine;N,N-Bis(2-chloroethane)amine; N,N-Bis(2-chloroethyl)amine; N,N-Bis(b-chloroethyl)amine; Nor-HN2;Nor-N-mustard; Nor-mechlorethamine; Nor-mustard; Nor-nitrogen mustard; b,b-Dichlorodiethylamine |
| Density: | 1.125g/cm3 |
| Boiling Point: | 204.2°Cat760mmHg |
| Flash Point: | 77.3°C |
| Safety: | Poison by intraperitoneal, subcutaneous, and intravenous routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic NOx and Cl−. |
| PSA: | 12.03000 |
| LogP: | 1.44450 |
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Chemistry
Chemistry informtion about Nornitrogen Mustard (CAS NO.334-22-5) is:
IUPAC Name: 2-Chloro-N-(2-Chloroethyl)Ethanamine
Synonyms: Nornitrogen Mustard ; Nor-N-Mustard ; 1,1'-Iminobis(2-Chloroethane) ; 2-Chloro-N-(2-Chloroethyl)Ethanamine ; Nor-Mustard
MF: C4H9Cl2N
MW: 142.026960 g/mol
Density: 1.125 g/cm3
Flash Point: 77.3 °C
Boiling Point: 204.2 °C at 760 mmHg
Vapour Pressure: 0.267 mmHg at 25°C
Enthalpy of Vaporization: 44.04 kJ/mol
Following is the molecular structure of Nornitrogen Mustard (CAS NO.334-22-5) is:
Uses
Nornitrogen Mustard (CAS NO.334-22-5) is common used in medicinal.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | intravenous | 5700ug/kg (5.7mg/kg) | gastrointestinal: other changes blood: leukopenia blood: other changes | Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965. |
| monkey | LDLo | intravenous | 11mg/kg (11mg/kg) | gastrointestinal: other changes blood: leukopenia blood: other changes | Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 201, 1965. |
| mouse | LD50 | intraperitoneal | 142mg/kg (142mg/kg) | Journal of Medicinal Chemistry. Vol. 8, Pg. 167, 1965. | |
| mouse | LD50 | subcutaneous | 20mg/kg (20mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 91, Pg. 224, 1947. | |
| rat | LD50 | intraperitoneal | 97mg/kg (97mg/kg) | Journal of Medicinal Chemistry. Vol. 8, Pg. 167, 1965. | |
| rat | LD50 | intravenous | 100mg/kg (100mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 1149, 1974. |
Safety Profile
Poison by intraperitoneal, subcutaneous, and intravenous routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic NOx and Cl−.