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Basic Information
CAS No.: 35604-67-2
Name: 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride
Molecular Structure:
Molecular Structure of 35604-67-2 (2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride)
Formula: C13H19 N O3 . Cl H
Molecular Weight: 273.76
Synonyms: Morpholine,2-[(2-ethoxyphenoxy)methyl]-, hydrochloride (9CI); 2-[(2-Ethoxyphenoxy)methyl]morpholiniumchloride; Catatrol; ICI 58834; Vicilan; Viloxazin hydrochloride; Viloxazinehydrochloride; Vivalan; Vivarint; Vivilan
EINECS: 252-638-6
Density: 1.061g/cm3
Melting Point: 178-180°C
Boiling Point: 350.5°Cat760mmHg
Flash Point: 144.3°C
Safety: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects by ingestion: hallucinations, distorted perceptions and convulsions or effect on seizure threshold. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as an antidepressant. See also VILOXAZINE.
PSA: 39.72000
LogP: 2.58330
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  • 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride

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Chemistry

IUPAC Name: 2-[(2-Ethoxyphenoxy)methyl]morpholine hydrochloride
The MF of 2-[(2-Ethoxyphenoxy)methyl]morpholine hydrochloride (CAS NO.35604-67-2) is C13H20ClNO3.

                                           
The MW of 2-[(2-Ethoxyphenoxy)methyl]morpholine hydrochloride (CAS NO.35604-67-2) is 273.7558.
Synonyms of 2-[(2-Ethoxyphenoxy)methyl]morpholine hydrochloride (CAS NO.35604-67-2): 2-((2-Ethoxyphenoxy)methyl)morpholine hydrochloride ; 2-(2-Ethoxyphenoxymethyl)-2,3,5,6-tetrahydro-1,4-oxazine hydrochloride ; Morpholine, 2-((2-ethoxyphenoxy)methyl)-, hydrochloride
Flash Point: 144.3 °C
Boiling Point: 350.5 °C
EINECS: 252-638-6

Uses

  2-[(2-Ethoxyphenoxy)methyl]morpholine hydrochloride (CAS NO.35604-67-2) is used as chemical reagent, fine chemicals, organic synthesis reagents, pharmaceutical intermediates.

Toxicity Data With Reference

1.    

orl-hmn TDLo:25 mg/kg/6D:CNS

     BMJOAE    British Medical Journal. 2 (1977),96.
2.    

ipr-rat LD50:162 mg/kg

     FRPSAX    Farmaco, Edizione Scientifica. 35 (1980),812.
3.    

orl-mus LD50:1 g/kg

     MEIEDD    Merck Index. 10 (1983),1427.
4.    

ipr-mus LD50:162 mg/kg

     FRPSAX    Farmaco, Edizione Scientifica. 35 (1980),812.
5.    

ivn-mus LD50:60 mg/kg

     MEIEDD    Merck Index. 10 (1983),1427.

Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects by ingestion: hallucinations, distorted perceptions and convulsions or effect on seizure threshold. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as an antidepressant. See also VILOXAZINE.