357-08-4

The Naloxone hydrochloride, with the CAS registry number 357-08-4, is also known as Naloxone HCl. It belongs to the product categories of Intermediates & Fine Chemicals; Pharmaceuticals; Opioid Receptor and Opioid-Like Receptor; Opioids. Its EINECS registry number is 206-611-0. This chemical's molecular formula is C₁₉H₂₂ClNO₄ and molecular weight is 363.83528. Its systematic name is called (5α)-3,14-dihydroxy-17-prop-2-en-1-yl-4,5-epoxymorphinan-6-one hydrochloride. This chemical's classification codes are Antagonist [to narcotics]; Drug / Therapeutic Agent; Human Data; Reproductive Effect. This chemical can be used as antagonists of narcotics analgesics. In addition, it can relieve narcotics analgesics caused by respiratory inhibition and addiction.

Physical properties of Naloxone hydrochloride: (1)ACD/LogP: 1.45; (2)#H bond acceptors: 5; (3)#H bond donors: 2; (4)#Freely Rotating Bonds: 4; (5)Flash Point: 276.1 °C; (6)Enthalpy of Vaporization: 85.12 kJ/mol; (7)Boiling Point: 532.8 °C at 760 mmHg; (8)Vapour Pressure: 3.49E-12 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
(2)Isomeric SMILES: C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl
(3)InChI: InChI=1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,14,17,21,23H,1,5-10H2;1H/t14-,17+,18+,19-;/m1./s1
(4)InChIKey: RGPDIGOSVORSAK-STHHAXOLSA-N

The toxicity data is as follows: