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35943-35-2

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Basic Information
CAS No.: 35943-35-2
Name: API-2
Article Data: 4
Molecular Structure:
Molecular Structure of 35943-35-2 (API-2)
Formula: C13H16 N6 O4
Molecular Weight: 320.308
Synonyms: 6-Amino-4-methyl-8-(b-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyrimido[4,5-c]pyridazine;API 2; NSC 154020; TCN; Triciribine
Density: 2.02g/cm3
Melting Point: 207 °C (decomp)
Boiling Point: 718.5°Cat760mmHg
Flash Point: 388.3°C
Safety: Poison by subcutaneous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
PSA: 144.47000
LogP: -0.90710
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Chemistry

IUPAC Name: Triciribine
The MF of Triciribine (CAS NO.35943-35-2) is C13H16N6O4.

                      
The MW of Triciribine (CAS NO.35943-35-2) is 320.3.
Synonyms of Triciribine (CAS NO.35943-35-2): 1,5-Dihydro-5-methyl-1-b-D-ribofuranosyl-1,4,5,6,8-pentaazaacennaphthylen-3-amine ; 5-Methyl-1-b-D-ribofuranosyl-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine
Product Categories: Protein Kinase 
Index of Refraction: 1.928 
Density: 2.02 g/ml 
Flash Point: 388.3 °C
Boiling Point: 718.5 °C

Uses

   Triciribine (CAS NO.35943-35-2) is used in medicine, pesticide manufacturing.

Toxicity Data With Reference

1.    

dni-mus:leu 90 nmol/L

     BCPCA6    Biochemical Pharmacology. 27 (1978),233.
2.    

oms-mus:leu 90 nmol/L

     BCPCA6    Biochemical Pharmacology. 27 (1978),233.
3.    

oms-mus:leu 100 nmol/L

     CNREA8    Cancer Research. 45 (1985),6355.
4.    

ipr-mus LD50:150 mg/kg

     NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
5.    

scu-mus LD50:199 mg/kg

     NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .

Safety Profile

Poison by subcutaneous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.