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Basic Information
CAS No.: 380843-75-4
Name: Bosutinib
Molecular Structure:
Molecular Structure of 380843-75-4 (Bosutinib)
Formula: C26H29Cl2N5O3
Molecular Weight: 530.454
Synonyms: 4-[(2,4-dichloro-5-methoxy-phenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile;3-Quinolinecarbonitrile, 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-;Bosutinib [USAN];4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile;SKI-606;Bosutinib(TINIBS );
EINECS: 700-455-1
Density: 1.36 g/cm3
Melting Point: 116-120 °C
Boiling Point: 649.7 °C at 760 mmHg
Flash Point: 346.7 °C
Appearance: white powder
Hazard Symbols: Xi
Risk Codes: 36
Safety: 26
PSA: 82.88000
LogP: 5.13918
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    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

    TaiChem was established in 2015 and registered in China medical city - Taizhou, Jiangsu Province. The company has about 1800 square meters of class A plant facility. TaiChem focuse

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    380843-75-4

    Bosutinib

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    Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Qui

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  • Bosutinib

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    380843-75-4

    Bosutinib

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 18.0-20.0

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    Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries. pharmaceutical field in

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    Address:No.1581-12,Jinshui Road, Licang, Qingdao,China

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    380843-75-4

    Bosutinib

    Min.Order: 1 Milligram

    FOB Price:  USD $ 10.0-10.0

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  • Bosutinib

  • Casno:

    380843-75-4

    Bosutinib

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your evaluation & Form

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    380843-75-4

    Bosutinib

    Min.Order: 25 Milligram

    FOB Price:  USD $ 10.0-10.0

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Specification

1. Introduction of Bosutinib
Bosutinib is one kind of white powder. The IUPAC Name of it is 4-(2,4-Dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile. It belongs to API;Aromatics Compounds. It may in EP Standard or Standard Enterprise. The Classification Code of it is Antineoplastic (Src kinase inhibitor); Antineoplastic Agents; Antineoplastic [Src kinase inhibitor].

2. Properties of Bosutinib
Physical properties about Bosutinib are:
(1)Index of Refraction: 1.651; (2)Density: 1.36 g/cm3; (3)Flash Point: 346.7 °C; (4)Melting point: 116-120 °C; (5)Enthalpy of Vaporization: 95.77 kJ/mol; (6)Boiling Point: 649.7 °C at 760 mmHg; (7)Vapour Pressure: 9.15E-17 mmHg at 25 °C.

3. Structure Descriptors of Bosutinib
(1)InChI: InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)
(2)InChIKey: InChIKey=UBPYILGKFZZVDX-UHFFFAOYSA-N
(3)Smiles: c1(cc2ncc(C#N)c(Nc3cc(OC)c(Cl)cc3Cl)c2cc1OC)OCCCN1CCN(CC1)C

4. Uses of Bosutinib
Bosutinib (CAS NO.380843-75-4) has been used for API. It is a tyrosine kinase inhibitor undergoing research for use in the treatment of CML. It is also used in the treatment of cancer use in the treatment of cancer. Some commercial stocks of bosutinib have recently been found to have the incorrect chemical structure, calling the biological results obtained with them into doubt.