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390-28-3

Basic Information
CAS No.: 390-28-3
Name: methoxamine
Article Data: 6
Molecular Structure:
Molecular Structure of 390-28-3 (methoxamine)
Formula: C11H17 N O3
Molecular Weight: 211.261
Synonyms: Benzylalcohol, a-(1-aminoethyl)-2,5-dimethoxy-(8CI); Methoxamine (6CI); 2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol;Methoxamin; a-(1-Aminoethyl)-2,5-dimethoxybenzylalcohol
EINECS: 206-867-3
Density: g/cm3
Melting Point: 85-86 °C
Boiling Point: 368.4°Cat760mmHg
Flash Point: 176.6°C
PSA: 64.71000
LogP: 1.78470
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Chemistry

Molecular Structure of Methoxamedrine (CAS No.390-28-3):

Molecular Formula: C11H17NO
Molecular Weight: 211.2576
IUPAC Name: 2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol  
CAS No: 390-28-3
H bond acceptors: 4
H bond donors: 3
Freely Rotating Bonds: 6
Polar Surface Area: 30.93 Å2
Index of Refraction: 1.534
Molar Refractivity: 58.82 cm3
Molar Volume: 189 cm3
Surface Tension: 41.1 dyne/cm
Density: 1.117 g/cm3
Flash Point: 176.6 °C
Enthalpy of Vaporization: 64.88 kJ/mol
Boiling Point: 368.4 °C at 760 mmHg
Vapour Pressure: 4.47E-06 mmHg at 25°C
InChI: InChI=1/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3
InChIKey: WJAJPNHVVFWKKL-UHFFFAOYAM
Std. InChI: InChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,12H2,1-3H3
Std. InChIKey: WJAJPNHVVFWKKL-UHFFFAOYSA-N
Classification Code: Adrenergic Agents;Adrenergic Agonists;Adrenergic alpha-agonists;Autonomic Agents;Cardiovascular Agents;Drug / Therapeutic Agent;Neurotransmitter Agents;Peripheral Nervous System Agents;Sympathomimetics;Vasoconstrictor agents

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 69mg/kg (69mg/kg) CARDIAC: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 160, Pg. 22, 1968.
mouse LD50 oral 30mg/kg (30mg/kg)   Japanese Journal of Toxicology. Vol. 4, Pg. 105, 1991.
mouse LD50 subcutaneous 30mg/kg (30mg/kg)   Japanese Journal of Toxicology. Vol. 4, Pg. 105, 1991

Specification

   Methoxamedrine (CAS No.390-28-3), its synonyms are 2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol ; a-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol ; Benzenemethanol, a-(1-aminoethyl)-2,5-dimethoxy- (9CI) ; Benzyl alcohol, a-(1-aminoethyl)-2,5-dimethoxy- (8CI) ; Methoxamine (6CI);Methoxamin ; α-(1-Aminoethyl)-2,5-dimethoxybenzenemethanol ; α-(1-Aminoethyl)-2,5-dimethoxybenzyl alcohol