CAS No.395-28-8,isoxsuprine Suppliers

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Basic Information

Molecular Structure:
CAS No.:	395-28-8
Name:	isoxsuprine

Formula:	C18H23 N O3
Molecular Weight:	301.386
Synonyms:	Benzylalcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]- (6CI,8CI);1-(p-Hydroxyphenyl)-2-(1-methyl-2-phenoxyethylamino)-1-propanol;2-(3-Phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanol;Isoxsuprine;erythro-1-(p-Hydroxyphenyl)-2-(a-methyl-b-phenoxyethylamino)propanol;p-Hydroxy-N-(1-methyl-2-phenoxyethyl)norephedrine;p-Hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)-amino]ethyl]benzylalcohol;
EINECS:	206-898-2
Density:	1.146g/cm³
Melting Point:	102.5-103.5°
Boiling Point:	484.2°Cat760mmHg
Flash Point:	246.6°C
Safety:	Poison by ingestion, intravenous and intraperitoneal routes. A human teratogen. Human reproductive effects by ingestion: uterus, cervix and vagina effects. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x. Used to delay premature parturition (labor) and to accelerate fetal lung development.
PSA:	61.72000
LogP:	3.26210

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Chemistry

IUPAC Name: 4-[1-hydroxy-2-(1-phenoxypropan-2-ylamino)propyl]phenol
Synonyms: Lsoxsuprine ; 1-(p-Hydroxyphenyl)-2-(1-methyl-2-phenoxyethylamino)-1-propanol ; Benzenemethanol, 4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]- (9CI) ; Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]- (6CI, 8CI) ; erythro-1-(p-Hydroxyphenyl)-2-(a-methyl-b-phenoxyethylamino)propanol ; p-Hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)-amino]ethyl]benzyl alcohol ; p-Hydroxy-N-(1-methyl-2-phenoxyethyl)norephedrine
EINECS: 206-898-2
Density: 1.146 g/cm3
Flash Point: 246.6 °C
Index of Refraction: 1.58
Surface Tension: 46.9 dyne/cm
Enthalpy of Vaporization: 78.94 kJ/mol
Boiling Point: 484.2 °C at 760 mmHg
Vapour Pressure: 3.45E-10 mmHg at 25°C
Molecular Formula of Isoxsuprine (CAS NO.395-28-8 ) : C₁₈H₂₃NO₃
Molecular Weight: 301.3801 g/mol
Molecular Structure of Isoxsuprine (CAS NO.395-28-8 ) :

Toxicity Data With Reference

1.	orl-mus LD50:200 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1992.
2.	ipr-mus LD50:118 mg/kg	FRPSAX Farmaco, Edizione Scientifica. 38 (1983),571.
3.	ivn-mus LD50:48 mg/kg	EJMCA5 European Journal of Medicinal Chemistry. Chimie Therapeutique. 10 (1975),291.

Safety Profile

Poison by ingestion, intravenous and intraperitoneal routes. A human teratogen. Human reproductive effects by ingestion: uterus, cervix and vagina effects. An experimental teratogen. Experimental reproductive effects. When heated to decomposition Isoxsuprine (CAS NO.395-28-8 ) emits toxic fumes of NO_x. Used to delay premature parturition (labor) and to accelerate fetal lung development.

Specification

Classification Code of Isoxsuprine (CAS NO.395-28-8 ) : Adrenergic Agents;Adrenergic Agonists;Adrenergic beta-agonists;Autonomic Agents;Cardiovascular Agents;Human Data;Neurotransmitter Agents;Peripheral Nervous System Agents;
Reproductive Control Agents;Reproductive Effect;Sympathomimetics;Tocolytic agents;Vasodilator agents