404-82-0

Fenfluramine hydrochloride is a drug that suppresses appetite by altering brain levels of serotonin, formerly used in the management of obesity. With the CAS NO.404-82-0, it is also called Phenfluoramine hydrochloride; Ponderal; Ponderax; Pondimin.  And it should be stored in airtight containers.

Physical properties about Fenfluramine hydrochloride are: (1)ACD/LogP: 3.047; (2)ACD/LogD (pH 5.5): -0.04; (3)ACD/LogD (pH 7.4): 0.40; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 2.45; (8)#H bond acceptors: 1 ; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 4; (11)Flash Point: 100.8 °C ; (12)Enthalpy of Vaporization: 48.01 kJ/mol; (13)Boiling Point: 243.1 °C at 760 mmHg; (14)Vapour Pressure: 0.0327 mmHg at 25°C

Uses of Fenfluramine hydrochloride: Fenfluramine hydrochloride is used as slimming products. Apply to simple obesity. The blood drug levels reached steady state after 3-4d, resulting in efficacy. It is a compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.

When you are using this chemical, please be cautious about it as the following:
1. Keep container tightly closed;
2. Keep away from sources of ignition - No smoking;
3. Wear suitable protective clothing and gloves;
4. In case of accident or if you feel unwell, seek medical advice immediately (show label where possible);

You can still convert the following datas into molecular structure:
(1)InChI=1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H;
(2)InChIKey=ZXKXJHAOUFHNAS-UHFFFAOYSA-N;
(3)Smilesc1(cccc(c1)C(F)(F)F)C[C@@H](C)NCC.Cl;

The toxicity data is as follows: