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43033-72-3

Basic Information
CAS No.: 43033-72-3
Name: Levomethadyl acetate hydrochloride
Article Data: 1
Molecular Structure:
Molecular Structure of 43033-72-3 (Levomethadyl acetate hydrochloride)
Formula: C23H31 N O2 . Cl H
Molecular Weight: 389.966
Synonyms: Benzeneethanol,b-[(2S)-2-(dimethylamino)propyl]-a-ethyl-b-phenyl-, acetate (ester),hydrochloride, (aS)-(9CI);Benzeneethanol, b-[2-(dimethylamino)propyl]-a-ethyl-b-phenyl-,acetate (ester), hydrochloride, [S-(R*,R*)]-;LAAM hydrochloride;LAAM-HCl;Levacetyl methadol hydrochloride;Levomethadyl acetate hydrochloride;MK 790;Orlaam;l-Acetylmethadol hydrochloride;l-a-Acetylmethadol hydrochloride;a-l-Acetylmethadol hydrochloride;
Density: g/cm3
Melting Point: 215°
Boiling Point: 456°Cat760mmHg
Flash Point: 130°C
Hazard Symbols: T
Risk Codes: 25-36/37/38
Safety: Poison by ingestion and parenteral routes. Questionable carcinogen with experimental carcinogenic data. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.
PSA: 29.54000
LogP: 5.45660
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Chemistry

Product Name: Levomethadyl acetate hydrochloride
CAS Registry Number: 43033-72-3
IUPAC Name: [(3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate hydrochloride
Molecular Weight: 389.95868 [g/mol]
Molecular Formula: C23H32ClNO2
H-Bond Donor: 1
H-Bond Acceptor: 3 
Flash Point: 130 °C
Enthalpy of Vaporization: 71.58 kJ/mol
Boiling Point: 456 °C at 760 mmHg
Vapour Pressure: 1.68E-08 mmHg at 25°C
Other Registry Number: 5989-56-0
Following is the molecular structure of Levomethadyl acetate hydrochloride (CAS NO.43033-72-3) is:

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 71mg/kg (71mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Fundamental and Applied Toxicology. Vol. 11, Pg. 626, 1988.
mouse LD50 parenteral 11mg/kg (11mg/kg) BEHAVIORAL: ANALGESIA Journal of Pharmacology and Experimental Therapeutics. Vol. 145, Pg. 11, 1964.
mouse LD50 subcutaneous 110mg/kg (110mg/kg)   Journal of Organic Chemistry. Vol. 17, Pg. 321, 1952.
rat LD50 oral 29mg/kg (29mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
JAT, Journal of Applied Toxicology. Vol. 14, Pg. 435, 1994.
rat LD50 subcutaneous 16mg/kg (16mg/kg)   JAT, Journal of Applied Toxicology. Vol. 14, Pg. 435, 1994.

Safety Profile

Poison by ingestion and parenteral routes. Questionable carcinogen with experimental carcinogenic data. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl.

Specification

 Levomethadyl acetate hydrochloride , its cas register number is 43033-72-3. It also can be called Levomethadyl acetate hydrochloride [USAN] ; (-)-(3S,6S)-6-(Dimethylamino)-4,4-diphenyl-3-heptanol acetate (ester), hydrochloride ; Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester), hydrochloride, (S-(R*,R*))- ; CCRIS 3321 ; LAAM hydrochloride ; Levacetyl methadol hydrochloride ; Levomethadyl acetate HCl ; Levomethadyl acetate hydrochloride ; MK 790 ; Orlaam ; alpha-l-Acetylmethadol hydrochloride ; l-Acetylmethadol hydrochloride ; l-alpha-Acetylmethadol hydrochloride ; 3-Heptanol, 6-(dimethylamino)-4,4-diphenyl-, acetate (ester), hydrochloride, (3S,6S)-(-)- ; Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester), hydrochloride, (S-(R*,R*))- ; L-alpha-Acetylmethadol hydrochloride .