CAS No.492-08-0,PACHYCARPINE Suppliers

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Basic Information

Molecular Structure:
CAS No.:	492-08-0
Name:	PACHYCARPINE
Article Data:	13

Formula:	C₁₅H₂₆N₂
Molecular Weight:	234.385
Synonyms:	Pachycarpine;
Density:	1.08g/cm³
Melting Point:	201oC
Boiling Point:	340.9°Cat760mmHg
Flash Point:	148.3°C
Safety:	Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.
PSA:	6.48000
LogP:	2.22090

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Chemistry

Chemistry informtion about Pachycarpine (CAS NO.492-08-0) is:
Synonyms: Pachycarpine ; (1r,2s,9r,10r)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]Heptadecane ; (7r)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7β,14β-Methano-2h,6h-Dipyrido[1,2-A:1',2'-E][1,5]Diazocine ; D-Sparteine ; Sparteine D-Isomer
MF: C₁₅H2₆N₂
MW: 234.38
Density: 1.08 g/cm³
Flash Point: 148.3 °C
Boiling Point: 340.9 °C at 760 mmHg
Vapour Pressure: 8.34E-05 mmHg at 25°C
Enthalpy of Vaporization: 58.45 kJ/mol
Following is the molecular structure of Pachycarpine (CAS NO.492-08-0) is:

Uses

Pachycarpine (CAS NO.492-08-0) has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest because of genetic variation in its metabolism.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	89100ug/kg (89.1mg/kg)	behavioral: tremor behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea	Shaanxi Xinyiyao. Shaanxi New Medical. Vol. 11(6), Pg. 53, 1982.
mouse	LD50	intravenous	26mg/kg (26mg/kg)		"Ganglion-Blocking and Ganglion-Stimulation Agents," Kharkevich, D.A., Moscow, First Moscow Medical Institute, 1967Vol. -, Pg. 175, 1967.
mouse	LD50	subcutaneous	90mg/kg (90mg/kg)	behavioral: muscle contraction or spasticity) lungs, thorax, or respiration: dyspnea	Farmakologiya i Toksikologiya Vol. 21(5), Pg. 46, 1958.

Safety Profile

Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.

Specification

Pachycarpine (CAS NO.492-08-0) is an alkaloid isolated from lupin beans, Lupinus luteus and Lupinus niger.