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CAS No.: 522-00-9
Name: ETHOPROPAZINE
Molecular Structure:
Molecular Structure of 522-00-9 (ETHOPROPAZINE)
Formula: C19H24 N2 S
Molecular Weight: 312.479
Synonyms: Phenothiazine,10-[2-(diethylamino)propyl]- (8CI); Prophenamine (7CI); (?à)-Ethopropazine; (?à)-Profenamine;10-(2-Diethylamino-1-propyl)phenothiazine;10-(2-Diethylamino-2-methylethyl)phenothiazine;10-(2-Diethylaminopropyl)phenothiazine;2-Diethylamino-1-propyl-N-dibenzoparathiazine; Ethapropazine; Ethopromazine;Ethopropazine; Isopthazine; Isothazine; Isothiazine;N,N-Diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine; Parkin; Parsidol;Phenopropazine; Profenamine; RP 3356; SC 2538; W 483
Density: 1.098g/cm3
Melting Point: 53-55°
Boiling Point: 430.1°Cat760mmHg
Flash Point: 213.9°C
Safety: Poison by ingestion, subcutaneous, and intravenous routes. An anticholinergic agent used to treat Parkinson's disease. When heated to decomposition it emits very toxic fumes of NOx and SOx.
PSA: 31.78000
LogP: 5.08460
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Toxicity Data With Reference

1.   

scu-rat LD50:200 mg/kg

    PSCBAY    Psychopharmacology Service Center, Bulletin. 2 (1963),17.
2.   

ivn-rat LD50:15 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,41.
3.   

orl-mus LD50:300 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 111 (1972),293.
4.   

scu-mus LD50:500 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,41.
5.   

ivn-mus LD50:50 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,41.
6.   

scu-rbt LD50:200 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,41.
7.   

ivn-rbt LD50:15 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,41.

Safety Profile

Poison by ingestion, subcutaneous, and intravenous routes. An anticholinergic agent used to treat Parkinson's disease. When heated to decomposition it emits very toxic fumes of NOx and SOx.