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Basic Information
CAS No.: 522-40-7
Name: FOSFESTROL
Molecular Structure:
Molecular Structure of 522-40-7 (FOSFESTROL)
Formula: C18H22O8P2
Molecular Weight: 428.315
Synonyms: stilboestrolbis(dihydrogenphosphate)
Density: 1.433g/cm3
Melting Point: 250.5°C
Boiling Point: 648.7°Cat760mmHg
Flash Point: 346.1°C
Safety: Moderately toxic by intravenous route. An experimental teratogen. Other experimental reproductive effects. Human systemic effects by intravenous routes: blood pressure lowering, blood clotting factor change, sweating. Mutation data reported. When heated to decomposition it emits toxic fumes of POx. See also DIETHYLSTILBESTROL DIPALMITATE; DIETHYLSTILBESTROL DIPROPIONATE.
PSA: 153.14000
LogP: 4.36040
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Chemistry

IUPAC Name: [4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate
Empirical Formula: C18H22O8P2
Molecular Weight: 428.31 g/mol
Index of Refraction: 1.609
Density: 1.433 g/cm3
Flash Point: 346.1 °C
Enthalpy of Vaporization: 100.5 kJ/mol
Boiling Point: 648.7 °C at 760 mmHg
Vapour Pressure: 1.03E-17 mmHg at 25 °C 
Structure of  Diethylstilbestrol diphosphate [USAN] (CAS NO.522-40-7):

 

Toxicity Data With Reference

1.    

cyt-mus-ivn 10 mg/kg

    ENMUDM    Environmental Mutagenesis. 1 (1979),184.
2.    

dnd-ham:ovr 400 nmol/L

    ENMUDM    Environmental Mutagenesis. 1 (1979),163.
3.    

ivn-man TDLo:11 mg/kg/3D-I:BPR,SKN

    SMJOAV    Southern Medical Journal. 75 (1982),248.
4.    

ivn-mus LD50:630 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),666.

Consensus Reports

EPA Genetic Toxicology Program.

Safety Profile

 Moderately toxic by intravenous route.An experimental teratogen.Other experimental reproductive effects.Human systemic effects by intravenous routes:blood pressure lowering,blood clotting factor change,sweating. Mutation data reported.When heated to decomposition, Diethylstilbestrol diphosphate [USAN] (CAS NO.522-40-7) emits toxic fumes of POx. See also DIETHYLSTILBESTROL DIPALMITATE; DIETHYLSTILBESTROL DIPROPIONATE.

Specification

 Diethylstilbestrol diphosphate [USAN] ,its cas register number is 522-40-7.It also can be called Fosfestrol ; Diethylstilbesterol diphosphate ; Stilbestrol diphosphate and so on.At the same time,it is practically insoluble in water and was Odorless off-white crystalline powder.