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52665-74-4

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Basic Information
CAS No.: 52665-74-4
Name: MANUMYCIN A
Molecular Structure:
Molecular Structure of 52665-74-4 (MANUMYCIN A)
Formula: C31H38 N2 O7
Molecular Weight: 550.6426
Synonyms: 2,4-Decadienamide,N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-,(2E,4E,6R)- (9CI); Manumycin (7CI); 7-Oxabicyclo[4.1.0]heptane,2,4-decadienamide deriv.; (-)-Manumycin A; Manumycin A; NSC 622141; UCF 1C
Density: 1.26 g/cm3
Boiling Point: 863.6 °C at 760 mmHg
Flash Point: 476.1 °C
Solubility: Soluble in Chloroform.
Appearance: Yellow powder
PSA: 145.33000
LogP: 4.48570
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Chemistry

IUPAC Name:(2E,4E)-N-[2-hydroxy-2-[(1E,3E,5E)-7-[(2-hydroxy-5-
oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-
5-oxo-7-oxabicyclo[4.1.0]hept-3-en-4-yl]-2,4,6-trimethyldeca-
2,4-dienamide
Synonyms: Manumycin A, streptomyces parvulus ; Manumycin ; Manumycin A from streptomyces parvulus ; N-[5-Hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyldeca-2,4-dienamide
Product Categories: Farnesyl transferase, RasG Proteins and Cyclic Nucleotides;D to;Enzyme Inhibitors by Enzyme;G Protein Function;Post-translational Modification
CAS NO: 52665-74-4
Molecular Formular of Manumycin A (CAS NO.52665-74-4) :C31H38N2O7
Molecular Weight of Manumycin A (CAS NO. 52665-74-4) : 550.64
Molecular Structure of Manumycin A (CAS NO. 52665-74-4) :
Mol File: 52665-74-4.mol
Index of Refraction: 1.604
Surface Tension: 57.1 dyne/cm
Density: 1.26 g/cm3
Flash Point: 476.1 °C
Enthalpy of Vaporization: 142.64 kJ/mol
Boiling Point: 863.6 °C at 760 mmHg
Vapour Pressure: 8.81E-35 mmHg at 25°C
Storage temp: 2-8°C

Uses

  Manumycin A (CAS NO. 52665-74-4) , inhibitor of ras Farnesyltransferase, inhibits proliferation and migration of rat vascular smooth muscle cells.

Safety Profile

WGK Germany 3