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53-59-8

Basic Information
CAS No.: 53-59-8
Name: Triphosphopyridine nucleotide
Article Data: 28
Molecular Structure:
Molecular Structure of 53-59-8 (Triphosphopyridine nucleotide)
Formula: C21H28 N7 O17 P3
Molecular Weight: 743.411
Synonyms: Adenosine5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'®5'-ester with3-(aminocarbonyl)-1-b-D-ribofuranosylpyridinium hydroxide, inner salt; Pyridinium,3-carbamoyl-1-b-D-ribofuranosyl-,hydroxide, 5'®5'-esterwith adenosine 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate), innersalt (8CI); 52: PN: WO2004076659 FIGURE: 7 claimed sequence;Adenine-nicotinamide dinucleotide phosphate; Codehydrase II; CodehydrogenaseII; Coenzyme II; Cozymase II; NAD phosphate; NADP; NADP+; Nicotinamide-adeninedinucleotide phosphate; TPN; TPN (nucleotide); Triphosphopyridine nucleotide; b-NADP; b-Nicotinamide adeninedinucleotide phosphate; b-TPN
EINECS: 200-178-1
Density: g/cm3
Boiling Point: °Cat760mmHg
Flash Point: °C
Hazard Symbols:
Risk Codes: R36/37/38   
Safety: Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx and POx.
PSA: 397.05000
LogP: -1.17920
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    CAS No.: 53-59-8 Other Names: beta-Nicotinamide adenine dinucleotide phosphate; beta-NADP MF: C21H28N7O17P3 EINECS No.: n/a Place of Origin:shannxi, China (Mainland) Type:

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    CAS: 53-59-8 EINECS: 200-178-1 Chemical formula: C21H28N7O17P3 Molecular weight: 743.41 Solubility: H2O: 50mg/mL, clear, slightly yellow Acidity coefficient: pKa1 3.9; PKa2 6.1 (at 25 ℃) Storage conditions: Keep in dark place, Inert atmosphere, Store

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Chemistry

Product Name: Codehydrogenase II (CAS NO.53-59-8)


Molecular Formula: C21H28N7O17P3
Molecular Weight: 743.41g/mol
Mol File: 53-59-8.mol
Einecs: 200-178-1
XLogP3: -7.1
H-Bond Donor: 8
H-Bond Acceptor: 21

Uses

 Codehydrogenase II (CAS NO.53-59-8) is the living body as a coenzyme necessary for the biochemical and pharmaceutical research.

Production

Fresh Yanggan filtered through the grinding treatment, 80 °C hot water extraction, trichloroacetic acid treatment, by the soda and to pH5-6, centrifugal sedimentation washing, crude purified by cation exchange resin replacement, shaved-eluting, refined drying too.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 3166mg/kg (3166mg/kg)   Pharmaceutical Chemistry Journal Vol. 20, Pg. 160, 1986.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Safety Information of Codehydrogenase II (CAS NO.53-59-8):
Hazard Codes: Xi
Risk Statements: 36/37/38 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin
Safety Statements: 26-36
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing

Specification

 Codehydrogenase II ,its CAS NO. is 53-59-8,the synonyms is Triphosphopyridine nucleotide ; 2'-(Dihydrogenphosphate),5'.fwdarw.'-adenosine5'-(trihydrogendiphosphate ; Beta-tpn ; Codehydraseii ; Cozymaseii ; Enosine2'-(dihydrogenphosphate)5'-(trihydrogenpyrophosphate),innersalt ; Esterwith3-(aminocarbonyl)-1-beta-d-ribofuranosylpyridiniumhydroxide,inner ; Nadphosphate;pyridinium,3-carbamoyl-1-beta-d-ribofuranosyl-,hydroxide,5',5'-esterwithad .