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54025-36-4

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Basic Information
CAS No.: 54025-36-4
Name: 19-nortestosterone nitrosocarbamate
Molecular Structure:
Molecular Structure of 54025-36-4 (19-nortestosterone nitrosocarbamate)
Formula: C21H29 Cl N2 O4
Molecular Weight: 408.97
Synonyms: LS1727; Leo 1727; NSC 269719
Density: 1.43g/cm3
Boiling Point: 529.4°Cat760mmHg
Flash Point: 274°C
Safety: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of Cl− and NOx. See also N-NITROSO COMPOUNDS and CARBAMATES.
PSA: 76.04000
LogP: 4.85560
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Toxicity Data With Reference

1.   

orl-rat LD50:2190 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 49 (1981),290.
2.   

ipr-rat LD50:155 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 49 (1981),290.
3.   

ivn-rat LD50:4 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 49 (1981),290.
4.   

orl-mus LD10:1630 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 49 (1981),290.
5.   

ipr-mus LD50:98 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 49 (1981),290.
6.   

ivn-mus LD50:8 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 49 (1981),290.

Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of Cl− and NOx. See also N-NITROSO COMPOUNDS and CARBAMATES.