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Basic Information
CAS No.: 54504-70-0
Name: ETOFYLLINE CLOFIBRATE
Article Data: 4
Molecular Structure:
Molecular Structure of 54504-70-0 (ETOFYLLINE CLOFIBRATE)
Formula: C19H21 Cl N4 O5
Molecular Weight: 420.853
Synonyms: Duolip;Ethophylline clofibrate; Etofylline clofibrate; Etophylline clofibrate; ML1024; NSC 234348; Theofibrate
Density: 1.37g/cm3
Melting Point: 133-135°
Boiling Point: 615.8°C at 760 mmHg
Flash Point: 326.2°C
Safety: Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also ESTERS.
PSA: 97.35000
LogP: 1.48790
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Chemistry

IUPAC Name:  2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
The MF of Etofylline clofibrate (CAS NO.54504-70-0) is C19H21ClN4O5.

                
The MW of Etofylline clofibrate (CAS NO.54504-70-0) is 420.85.
Synonyms of Etofylline clofibrate (CAS NO.54504-70-0): Etofyllinclofibrate ; Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, 2-(7-theophyllinyl)ethyl ester
Index of Refraction: 1.617 
Density: 1.37 g/ml 
Flash Point: 326.2 °C
Boiling Point: 615.8 °C
EINECS: 259-191-6

Uses

  Etofylline clofibrate (CAS NO.54504-70-0) is used as lipid-lowering drugs.

Toxicity Data With Reference

1.    

orl-rat LD50:17,000 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 30 (1980),2023.
2.    

ipr-rat LD50:2830 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1173.
3.    

orl-mus LD50:1730 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 25 (1975),1686.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also ESTERS.