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Basic Information
CAS No.: 54504-70-0
Name: ETOFYLLINE CLOFIBRATE
Molecular Structure:
Molecular Structure of 54504-70-0 (ETOFYLLINE CLOFIBRATE)
Formula: C19H21 Cl N4 O5
Molecular Weight: 420.853
Synonyms: Duolip;Ethophylline clofibrate; Etofylline clofibrate; Etophylline clofibrate; ML1024; NSC 234348; Theofibrate
Density: 1.37g/cm3
Melting Point: 133-135°
Boiling Point: 615.8°C at 760 mmHg
Flash Point: 326.2°C
Safety: Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx. See also ESTERS.
PSA: 97.35000
LogP: 1.48790
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Chemistry

IUPAC Name:  2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
The MF of Etofylline clofibrate (CAS NO.54504-70-0) is C19H21ClN4O5.

                
The MW of Etofylline clofibrate (CAS NO.54504-70-0) is 420.85.
Synonyms of Etofylline clofibrate (CAS NO.54504-70-0): Etofyllinclofibrate ; Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, 2-(7-theophyllinyl)ethyl ester
Index of Refraction: 1.617 
Density: 1.37 g/ml 
Flash Point: 326.2 °C
Boiling Point: 615.8 °C
EINECS: 259-191-6

Uses

  Etofylline clofibrate (CAS NO.54504-70-0) is used as lipid-lowering drugs.

Toxicity Data With Reference

1.    

orl-rat LD50:17,000 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 30 (1980),2023.
2.    

ipr-rat LD50:2830 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),1173.
3.    

orl-mus LD50:1730 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 25 (1975),1686.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx. See also ESTERS.