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555-57-7

Basic Information
CAS No.: 555-57-7
Name: N-METHYL-N-PROPARGYLBENZYLAMINE
Article Data: 24
Molecular Structure:
Molecular Structure of 555-57-7 (N-METHYL-N-PROPARGYLBENZYLAMINE)
Formula: C11H13 N
Molecular Weight: 159.231
Synonyms: Benzenemethanamine,N-methyl-N-2-propynyl- (9CI); Benzylamine, N-methyl-N-2-propynyl- (6CI,8CI);Benzylmethylpropargylamine; Eudatin; N-Benzyl-N-methyl-2-propynylamine;N-Benzyl-N-methylpropargylamine; N-Methyl-N-2-propynylbenzenemethanamine;N-Methyl-N-2-propynylbenzylamine; N-Methyl-N-benzylpropynylamine;N-Methyl-N-propargylbenzylamine; Pargylamine; Pargylin; Pargyline; Supirdyl
EINECS: 209-101-6 (Base) 206-175
Density: 0.944
Melting Point: 156 - 160 C
Boiling Point: 86-88at4mmHg
Flash Point: 83
Solubility: white to off-white crystalline powder
Hazard Symbols: UN NO.
Risk Codes: R22;
Transport Information: small
PSA: 3.24000
LogP: 1.75160
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Chemistry

Chemistry informtion about N-Methyl-N-Propargylbenzylamine (CAS NO.555-57-7) is:
IUPAC Name: N-Benzyl-N-Methylprop-2-Yn-1-Amine
Synonyms: A 19120 ; Benzylamine, N-Methyl-N-2-Propynyl- ; Benzyl-Methyl-2-Propinylamin ; Eudatin ; Eutonyl ; Mo 911 ; N-Benzyl-N-Methyl-2-Propyn-1-Amine ; N-Benzyl-N-Methyl-2-Propynylamine
MF: C11H13N
MW: 159.23
EINECS: 209-101-6 
Density: 0.978 g/cm3
Flash Point: 83.9 °C
Boiling Point: 228.4 °C at 760 mmHg
Enthalpy of Vaporization: 46.5 kJ/mol 
Vapour Pressure: 0.0736 mmHg at 25°C
Refractive Index: n20/D 1.522(lit.)
Merck: 13,7110
Following is the molecular structure of N-Methyl-N-Propargylbenzylamine (CAS NO.555-57-7) is:

Production

Raw materials are 3-Chloropropyne--> N-Methylbenzylamine .

Toxicity Data With Reference

1.    

orl-chd TDLo:8750 µg/kg:NOSE,EYE,PUL

    34ZIAG    Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,452.
2.    

orl-rat LD50:300 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 14 (1971),913.
3.    

ipr-rat LD50:142 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),1068.
4.    

orl-mus LD50:680 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 14 (1971),913.
5.    

ipr-mus LD50:290 mg/kg

    THERAP    Therapie. 22 (1967),367.
6.    

scu-mus LD50:380 mg/kg

    BCPCA6    Biochemical Pharmacology. 17 (1968),369.
7.    

ivn-mus LD50:56 mg/kg

    CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#02420 .
8.    

orl-dog LD50:175 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),1068.
9.    

ipr-mky LD50:200 mg/kg

    ANYAA9    Annals of the New York Academy of Sciences. 107 (1963),1068.
10.    

ipr-cat LD50:200 mg/kg

    ANYAA9   

Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by ingestion: eye lachrymation, olfactory and pulmonary effects. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
Hazard Codes:
ToxicT
Risk Statements:
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
RTECS: DP6475000
HazardClass: 6.1(b)
PackingGroup: III

Specification

 N-Methyl-N-Propargylbenzylamine (CAS NO.555-57-7) is a clear yellow liquid.
First Aid Measures:
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Remove from exposure and move to fresh air immediately.