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56393-22-7

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Basic Information
CAS No.: 56393-22-7
Name: Pildralazine
Molecular Structure:
Molecular Structure of 56393-22-7 (Pildralazine)
Formula: C8H15 N5 O . 2 Cl H
Molecular Weight: 270.20
Synonyms: 3(2H)-Pyridazinone,6-[(2-hydroxypropyl)methylamino]-, hydrazone, dihydrochloride (9CI); Atensil;ISF 2123; Pildralazine dihydrochloride; Propildazine; Propyldazinehydrochloride
Density: 1.302g/cm3
Melting Point: 206-209° (dec)
Boiling Point: 486°Cat760mmHg
Flash Point: 247.7°C
Safety: Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl.
PSA: 87.30000
LogP: 1.95650
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Chemistry

IUPAC  Name: 1-[(6-hydrazinylpyridazin-3-yl)-Methylamino]propan-2-ol dihydrochloride      
Molecular Formula: C8H17Cl2N5O
Molecular Weight: 270.20
Freely Rotating Bonds: 5
Polar Surface Area: 44.73Å2
Flash Point: 247.7 °C
Enthalpy of Vaporization: 79.17 kJ/mol
Boiling Point: 486 °C at 760 mmHg
Vapour Pressure: 2.93E-10 mmHg at 25°C
 The Cas Register Number of  3-Hydrazino-6-((2-hydroxypropyl)-methylamino)pyridazine dihydrochloride is 56393-22-7 . The chemical synonyms of  3-Hydrazino-6-((2-hydroxypropyl)-methylamino)pyridazine dihydrochloride (CAS NO.56393-22-7) are 6-((2-Hydroxypropyl)methylamino)-3(2H)-pyridazinone hydrazone dihydrochloride ; Pidralazine ; Pildralazine dihydrochloride  and  Pildralazine HCl .The molecular structure of  3-Hydrazino-6-((2-hydroxypropyl)-methylamino)pyridazine dihydrochloride (CAS NO.56393-22-7) is
.

Uses

  3-Hydrazino-6-((2-hydroxypropyl)-methylamino)pyridazine dihydrochloride (CAS NO.56393-22-7) is used in organic synthesis.

Toxicity Data With Reference

1.    

orl-rat LD50:1230 mg/kg

     PLRCAT    Pharmacological Research Communications. 8 (1976),295.
2.    

ipr-rat LD50:355 mg/kg

     PLRCAT    Pharmacological Research Communications. 8 (1976),295.
3.    

orl-mus LD50:1170 mg/kg

     PLRCAT    Pharmacological Research Communications. 8 (1976),295.
4.    

ipr-mus LD50:600 mg/kg

     FRPSAX    Farmaco, Edizione Scientifica. 34 (1979),299.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and HCl.