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59-98-3

Basic Information
CAS No.: 59-98-3
Name: Tolazoline
Article Data: 40
Molecular Structure:
Molecular Structure of 59-98-3 (Tolazoline)
Formula: C10H12 N2
Molecular Weight: 160.219
Synonyms: 2-Imidazoline,2-benzyl- (8CI); Imidazoline, 2-benzyl- (6CI); 2-Benzyl-2-imidazoline;2-Benzyl-4,5-dihydro-1H-imidazole; 2-Benzyl-4,5-imidazoline;2-Benzylimidazoline; Artonil; Benzazoline; Benzidazol; Benzolin; Benzolin(vasodilator); Benzylimidazoline; Dilatol ASI; Divascol; Imidalin; Imidaline;Kasimid; Lambril; NSC 35110; Olitensol; Peripherine; Phenylmethylimidazoline;Prefaxil; Priscol; Priscoline; Tolazolin; Tolazoline; Vasimid; Vasodil
EINECS: 200-448-9
Density: 1.09g/cm3
Melting Point: 66-69 ºC
Boiling Point: 338.2°Cat760mmHg
Flash Point: 158.3°C
Hazard Symbols:
Risk Codes: R20/21/22;R36/37/38   
Safety: Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
PSA: 24.39000
LogP: 0.99520
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Chemistry

Chemical Name: Tolazoline
IUPAC NAME: 2-Benzyl-4,5-dihydro-1H-imidazole
CAS No.: 59-98-3
EINECS: 200-448-9
RTECS: NJ1925000
Molecular Formula: C10H12N2
Molecular Weight: 160.22 g/mol
Melting Point: 66-69 °C(lit.)
Density: 1.09 g/cm3
Flash Point: 158.3 °C
Boiling Point: 338.2 °C at 760 mmHg
Following is the structure of Benzidazol (CAS No.59-98-3):


The chemical synonymous of Benzidazol (CAS No.59-98-3) are Timtec-Bb Sbb003964 ; Tolazoline ; 2-Benzyl-2-Imidazoline ; Labotest-Bb Lt00772362 ; 2-Benzyl-2-Imidazolin ; 2-Benzyl-4,5-Dihydro-1h-Imidazole ; 2-Benzyl-4,5-Imidazoline ; 2-Benzyl-4,5-Imidazoline Hydrochloride

Toxicity Data With Reference

1.    

cyt-ham:lng 62,500 µg/L

    GMCRDC    Gann Monograph on Cancer Research. 27 (1981),95.
2.    

orl-mus LD50:350 mg/kg

    CPBTAL    Chemical and Pharmaceutical Bulletin. 22 (1974),514.
3.    

ipr-mus LD50:160 mg/kg

    PBPHAW    Progress in Biochemical Pharmacology. 1 (1965),542.
4.    

ivn-mus LD50:40 mg/kg

    RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 37 (1974),198.

Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: HarmfulXn
Risk Statements about Benzidazol (CAS No.59-98-3):
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements about Benzidazol (CAS No.59-98-3):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.