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Basic Information
CAS No.: 62-37-3
Name: chlormerodrin
Molecular Structure:
Molecular Structure of 62-37-3 (chlormerodrin)
Formula: C5H11ClHgN2O2
Molecular Weight: 367.22
Synonyms: CHLOROMERODRIN;
Melting Point: 152-153°
Boiling Point: 142°C
Safety: Poison by ingestion and intraperitoneal routes. A diuretic. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and Hg.
PSA: 64.35000
LogP: 1.35340
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Chemistry

IUPAC Name: [3-(Carbamoylamino)-2-methoxypropyl]-chloromercury
Synonyms of Chloromerodrin (CAS NO.62-37-3) : (3-(Chloromercuri)-2-methoxypropyl)urea ; Chlormerodrin ; Mercury, (3-((aminocarbonyl)amino)-2-methoxypropyl)chloro- ; Mercury, (3-((aminocarbonyl)amino)-2-methoxypropyl-C1,O3)chloro- (9CI) ; Mercury, chloro(2-methoxy-3-ureidopropyl)-
CAS NO:62-37-3
Molecular Formula  of Chloromerodrin (CAS NO.62-37-3):C5H11ClHgN2O2
Molecular Weight  of Chloromerodrin (CAS NO.62-37-3) :367.196
Molecular Structure  of Chloromerodrin (CAS NO.62-37-3) :

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 215mg/kg (215mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 143, Pg. 181, 1963.
mouse LDLo intraperitoneal 62500ug/kg (62.5mg/kg)   "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 5, Pg. 144, 1953.
mouse LDLo subcutaneous 60mg/kg (60mg/kg)   Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 46, Pg. 689, 1957.
rat LD50 oral 150mg/kg (150mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.

Consensus Reports

Mercury and its compounds are on the Community Right-To-Know List.

Safety Profile

Poison by ingestion and intraperitoneal routes. A diuretic. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC. When Chloromerodrin (CAS NO.62-37-3) is heated to decomposition, it emits very toxic fumes of Cl−, NOx, and Hg.

Standards and Recommendations

OSHA PEL: CL 0.1 mg(Hg)/m3 (skin)
ACGIH TLV: TWA 0.1 mg(Hg)/m3 (skin); BEI: 35 µg/g creatinine total inorganic mercury in urine preshift; 15 µg/g creatinine total inorganic mercury in blood at end of shift at end of workweek.
DFG MAK: Confirmed Animal Carcinogen with Unknown Relevance to Humans
NIOSH REL: (Organomercury): TWA 0.01 mg/m3; STEL 0.03 mg/m3 (skin)