624-83-9

IUPAC: Methylimino(oxo)methane 
 Methyl isocyanate (624-83-9) is also called for 4-04-00-00247 (Beilstein Handbook Reference) ; AI3-28280 ; BRN 0605318 ; CCRIS 1385 ; EINECS 210-866-3 ; HSDB 1165 ; Iso-cyanatomethane ; Isocyanate de methyle ; Isocyanate, methyl- ; Isocyanic acid, methyl ester ; Methane, isocyanato- ; Methyl carbonimide ; Methyl isocyanat ; Methyl isocyanate ; Methyl isocyanide ; Methylcarbylamine ; Methylisocyanaat ; Metil isocianato ; NSC 64323 ; RCRA waste number P064 ; TL 1450 ; UN 2480 ; RCRA waste no. P064 and so on.
Molecular Formula: C₂H₃NO
Molecular Weight: 57.05 
LogP: ACD/LogP: 0.83
XLogP: 1.60 
ACD/LogD (pH 5.5): 0.83 
ACD/LogD (pH 7.4): 0.83 
ACD/BCF (pH 5.5): 2.52 
ACD/BCF (pH 7.4): 2.52 
ACD/KOC (pH 5.5): 67.37 
ACD/KOC (pH 7.4): 67.37 
H bond acceptors: 2 
H bond donors: 0 
Freely Rotating Bonds: 0  
Index of Refraction: 1.393 
Molar Refractivity: 15.47 cm³ 
Molar Volume: 64.7 cm³ 
Surface Tension: 28.3 dyne/cm 
Density: 0.88 g/cm³ 
FEnthalpy of Vaporization: 26.84 kJ/mol 
Boiling Point: 35°C at 760 mmHg 
Vapour Pressure: 531 mmHg at 25°C
The molecular structure of Methyl isocyanate (624-83-9):

 Methyl isocyanate (624-83-9) is used as antisickling agents,which mean agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.

Reported in EPA TSCA Inventory.

Poison by inhalation, ingestion, and skin contact. Human systemic effects by inhalation: conjunctiva irritation, olfactory and pulmonary changes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. A severe eye, skin, and mucous membrane irritant and a sensitizer. It can be absorbed through the skin. Exposure to high concentrations of the vapor can cause blindness; lung damage, including edema, permanent fibrosis, emphysema, and bronchitis; and gynecological effects. Most deaths are a result of lung tissue damage. This was the predominant cause of death in the release of MIC in 1984 at Bhopal, India. Effects of cyanide poisoning have been noted but this may be due to impurities. A flammable liquid and a very dangerous fire hazard when exposed to heat, flame, or oxidizers. To fight fire, use spray, foam, CO₂, dry chemical. Exothermic reaction with water. When heated to decomposition it emits toxic fumes of NO_x and CN⁻. See also ISOCYANATES.

OSHA PEL: TWA 0.02 ppm (skin)
ACGIH TLV: TWA 0.02 ppm (skin)
DFG MAK: 0.01 ppm (0.025 mg/m³)
DOT Classification:  6.1; Label: Poison, Flammable Liquid; DOT Class: 3; Label: Flammable Liquid, Poison

For occupational chemical analysis use OSHA: #54.

Treatment of  Methyl isocyanate (624-83-9) in Wastewater, see as follows :
Total removal:                 29.33  percent
Total biodegradation:        0.07  percent
Total sludge adsorption:    1.35  percent
Total to air:                    27.91  percent
 (using 10000 hr Bio P,A,S)