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Basic Information
CAS No.: 6775-25-3
Name: 1-(3,6-dihydropyridin-1(2H)-yl)-3-(2-methylphenoxy)propan-2-ol hydrochloride (1:1)
Molecular Structure:
Molecular Structure of 6775-25-3 (1-(3,6-dihydropyridin-1(2H)-yl)-3-(2-methylphenoxy)propan-2-ol hydrochloride (1:1))
Formula: C15H21NO2•ClH
Molecular Weight: 283.798
Density: g/cm3
Boiling Point: 403°Cat760mmHg
Flash Point: 197.5°C
Safety: Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and HCl.
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Chemistry

IUPAC  Name: 1-(3,6-Dihydro-2H-pyridin-1-yl)-3-(2-methylphenoxy)propan-2-ol hydrochloride     
Molecular Formula: C15H21NO2•ClH
Molecular Weight: 283.83
Freely Rotating Bonds: 6
Polar Surface Area: 21.7 Å2
Flash Point: 197.5 °C
Enthalpy of Vaporization: 68.99 kJ/mol
Boiling Point: 403 °C at 760 mmHg
Vapour Pressure: 3.22E-07 mmHg at 25°C 
The Cas Register Number of  Tolpronine hydrochloride is 6775-25-3 .The chemical synonyms of  Tolpronine hydrochloride (CAS NO.6775-25-3) are 1-(1,2,3,6-Tetrahydropyridino)-3-o-tolyloxypropan-2-ol hydrochloride ;1-(2H)-Pyridineethanol, 3,6-dihydro-alpha-((2-methylphenoxy)methyl)-, hydrochloride  and  Proponesin hydrochloride .The molecular structure of  Tolpronine hydrochloride (CAS NO.6775-25-3) is.

Uses

 Tolpronine hydrochloride (CAS NO.6775-25-3) is used as pharmaceutical intermediate.

Toxicity Data With Reference

1.    

orl-rat LD50:340 mg/kg

     JPPMAB    Journal of Pharmacy and Pharmacology. 10 (1958),60.
2.    

scu-rat LD50:1030 mg/kg

     JPPMAB    Journal of Pharmacy and Pharmacology. 10 (1958),60.
3.    

orl-mus LD50:330 mg/kg

     JPPMAB    Journal of Pharmacy and Pharmacology. 10 (1958),60.
4.    

ipr-mus LD50:146 mg/kg

     MEIEDD    Merck Index. 10 (1983),1363.
5.    

scu-mus LD50:390 mg/kg

     JPPMAB    Journal of Pharmacy and Pharmacology. 10 (1958),60. JPPMAB    Journal of Pharmacy and Pharmacology. 10 (1958),60.

Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx and HCl.