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Basic Information
CAS No.: 71-82-9
Name: LEVALLORPHAN TARTRATE
Article Data: 1
Molecular Structure:
Molecular Structure of 71-82-9 (LEVALLORPHAN TARTRATE)
Formula: C19H25NO•C4H6O6
Molecular Weight: 433.502
Synonyms: 17-allyl-morphinan-3-otartrate(1:1)(salt);4a-iminoethanophenanthren-6-ol,11-allyl-1,3,4,9,10,10a-hexahydro-2h-1tar;levallorphanhydrogentartrate;levallorphantartrate;levallorphinetartrate;l-levallorphantartrate;lorfan;lorfantartrate
Melting Point: 176-177°
Boiling Point: 660.4°C at 760 mmHg
Flash Point: 353.2°C
Hazard Symbols: Xn
Risk Codes: R22
Safety: Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
PSA: 23.47000
LogP: 3.57450
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Chemistry

Product Name: Lorfan tartrate
Synonyms of Lorfan tartrate (CAS NO.71-82-9): Levallorphan tartrate [JAN] ; 17-Allylmorphinan-3-ol tartrate (1:1) (salt) ; 2H-10,4a-Iminoethanophenanthren-6-ol, 11-allyl-1,3,4,9,10,10a-hexahydro-, tartrate ; EINECS 200-767-3 ; Levallorphan tartrate ; Lorfan ; Morphinan-3-ol, 17-(2-propenyl)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1) (salt) ; Tartrate de levallorphane ; Tartrate de levallorphane [French] ; UNII-U0VSF7HTN0 ; l-Levallorphan tartrate ; Levallorphan hydrogen tartrate ; Morphinan-3-ol, 17-allyl-, tartrate (1:1) (salt)
CAS NO: 71-82-9 
Molecular Formula of Lorfan tartrate (CAS NO.71-82-9): C19H25NO 
Molecular Weight: 283.4079 
H bond acceptors: 2
H bond donors: 1
Freely Rotating Bonds: 3
Polar Surface Area: 23.47 Å2
Index of Refraction: 1.614
Molar Refractivity: 85.959 cm3
Molar Volume: 246.613 cm3
Surface Tension: 50.429 dyne/cm
Density: 1.149 g/cm3
Flash Point: 214.168 °C
Enthalpy of Vaporization: 71.608 kJ/mol
Boiling Point: 433.49 °C at 760 mmHg 
Molecular Structure:

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 168mg/kg (168mg/kg)   Drugs in Japan Vol. 6, Pg. 904, 1982.
mouse LD50 intravenous 42mg/kg (42mg/kg)   Drugs in Japan Vol. 6, Pg. 904, 1982.
mouse LD50 oral 350mg/kg (350mg/kg)   Drugs in Japan Vol. 6, Pg. 904, 1982.
mouse LD50 subcutaneous 200mg/kg (200mg/kg)   French Demande Patent Document. Vol. #2004420,
rat LD50 intravenous 40mg/kg (40mg/kg)   Drugs in Japan Vol. 6, Pg. 904, 1982.
rat LD50 oral 850mg/kg (850mg/kg)   Drugs in Japan Vol. 6, Pg. 904, 1982.
rat LD50 subcutaneous 870mg/kg (870mg/kg)   Drugs in Japan Vol. 6, Pg. 904, 1982.

Safety Profile

Hazard Codes of Lorfan tartrate (CAS NO.71-82-9): XnHarmful
Risk Statements: 22 
R22: Harmful if swallowed.
Safety Statements: 36 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: QD0480000
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.