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71030-37-0

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Basic Information
CAS No.: 71030-37-0
Name: (+/-)12-HETE
Article Data: 6
Molecular Structure:
Molecular Structure of 71030-37-0 ((+/-)12-HETE)
Formula: C20H32 O3
Molecular Weight: 320.472
Synonyms: 5,8,10,14-Eicosatetraenoicacid, 12-hydroxy-, (E,Z,Z,Z)-; (5Z,8Z,10E,14Z)-12-Hydroxy-5,8,10,14-eicosatetraenoicacid; 12-HETE; 12-Hydroxy-5,8,10,14-eicosatetraenoic acid;12-Hydroxyeicosatetraenoic acid
Density: 0.983 g/cmºC
Boiling Point: 464.5 °C at 760 mmHg
Flash Point: 155.7 °C
Safety: Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
PSA: 17.07000
LogP: 6.96710
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Chemistry

Chemical Name: (+/-)12-HETE
IUPAC NAME: (5E,8Z,10Z,14Z)-12-Hydroxyicosa-5,8,10,14-tetraenoic acid
CAS No.: 71030-37-0
Molecular Formula: C20H32O3
Molecular Weight: 320.47 g/mol
Density: 0.984 g/cm3
Flash Point: 262.8 °C
Boiling Point: 487.7 °C at 760 mmHg
Following is the structure of 12-Hydroxyeicosatetraenoic acid (CAS No.71030-37-0):


The chemical synonymous of 12-Hydroxyeicosatetraenoic acid (CAS No.71030-37-0) are (+/-)12-Hydroxyeicosa-5z,8z,10e,14z-Tetraenoic Acid ; (+/-)12-Hydroxy-5z,8z,10e,14z-Eicosatetraenoic Acid ; (+/-)12-Hete ; 10,14-Eicosatetraenoicacid,12-Hydroxy-,(E,Z,Z,Z)-8 ; 12-Hydroxyeicosatetraenoicacid ; (5e,8z,10z,14z)-12-Hydroxyicosa-5,8,10,14-Tetraenoic Acid ; (5z,8z,10e,14z)-12-Hydroxy-5,8,10,14-Icosatetraenoic Acid ; (5z,8z,10e,14z)-12-Hydroxyicosa-5,8,10,14-Tetraenoic Acid

Toxicity Data With Reference

1.    

dnd-hmn-lym 5 µmol/L

     CRNGDP    Carcinogenesis. 10 (1989),1029.
2.    

dni-hmn-oth 20 µmol/L

     CNREA8    Cancer Research. 45 (1985),561.

Safety Profile

Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.

Specification

12-Hydroxyeicosatetraenoic acid (CAS No.71030-37-0) is an eicosanoid. It is a metabolite of arachidonic acid produced by the action of the enzyme arachidonate 12-lipoxygenase.It is a highly selective ligand used to label mu opioid receptors.