Products Categories
| CAS No.: | 73-48-3 |
|---|---|
| Name: | BENDROFLUMETHIAZIDE |
| Molecular Structure: | |
|
|
|
| Formula: | C15H14F3N3O4S2 |
| Molecular Weight: | 421.421 |
| Synonyms: | 2H-1,2,4-Benzothiadiazine-7-sulfonamide,3-benzyl-3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide (6CI,8CI);3-Benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide;3-Benzyl-6-trifluoromethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide;6-Trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide;Aprinox;Be 724A;Bendrofluazide;Bentride;Benuron;Benzy-Rodiuran;Berkozide;Bristuron;Centyl;FT 81;Livesan;Naigaril;Naturetin;Neo-Rontyl;Niagaril;Orsile;Pluryl;Pluryle;Poliuron;Rauzide;Relan Beta;Salural;Sinesalin;Sodiuretic;Urlea; |
| EINECS: | 200-800-1 |
| Density: | 1.528 g/cm3 |
| Melting Point: | 205-207 °C |
| Boiling Point: | 602.1 °C at 760 mmHg |
| Flash Point: | 317.9 °C |
| Solubility: | 40mg/L(room temperature) |
| Appearance: | white solid |
| PSA: | 135.12000 |
| LogP: | 4.95410 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
- 488-23-31,2,3,4-Tetramethylbenzene
- 25103-58-6tert-Dodecylthiol
- 53786-28-02H-Benzimidazol-2-one,5-chloro-1,3-dihydro-1-(4-piperidinyl)-
- 1218-69-52-(2-Hydroxyphenyl)-4H-benzo[e][1,3]oxazin-4-one
- 18497-13-7Platinate(2-),hexachloro-, hydrogen, hydrate (1:2:6), (OC-6-11)-
- 25035-71-6Benzenesulfonamide, 4-methyl-, polymer with formaldehyde
- 38870-89-2Acetyl chloride,2-methoxy-
- 1007089-84-03-(Chloromethyl)-5-methylpyridine hydrochloride
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Chemistry
Product Name: Bendroflumethiazide (CAS NO.73-48-3)
Molecular Formula: C15H14F3N3O4S2
Molecular Weight: 421.41g/mol
Mol File: 73-48-3.mol
Einecs: 200-800-1
Boiling point: 602.1 °C at 760 mmHg
Flash Point: 317.9 °C
Density: 1.528 g/cm3
Surface Tension: 49.2 dyne/cm
Enthalpy of Vaporization: 89.59 kJ/mol
Vapour Pressure: 1.88E-14 mmHg at 25°C
XLogP3-AA: 1.2
H-Bond Donor: 3
H-Bond Acceptor: 10
Structure Descriptors of Bendroflumethiazide (CAS NO.73-48-3):
IUPAC Name: 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
Canonical SMILES: C1=CC=C(C=C1)CC2NC3=C(C=C(C(=C3)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N2
InChI: InChI=1S/C15H14F3N3O4S2/c16-15(17,18)10-7-11-13(8-12(10)26(19,22)23)27(24,25)21-14(20-11)6-9-4-2-1-3-5-9/h1-5,7-8,14,20-21H,6H2,(H2,19,22,23)
InChIKey: HDWIHXWEUNVBIY-UHFFFAOYSA-N
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 4800mg/kg (4800mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 238, Pg. 435, 1960. | |
| mouse | LD50 | intravenous | 395mg/kg (395mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 273, 1961. |
| mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Drugs in Japan Vol. 6, Pg. 781, 1982. | |
| women | TDLo | oral | 300ug/kg/3D-I (0.3mg/kg) | Lancet. Vol. 2, Pg. 634, 1986. |
Safety Profile
Poison by intravenous route. Human systemic effects by ingestion: convulsions and somnolence. Mutation data reported. When heated to decomposition it emits toxic fumes of F−, SOx, and NOx.
Specification
Bendroflumethiazide ,its CAS NO. is 73-48-3,the synonyms is (+-)-3-Benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide ; 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-dioxide ; 3-Benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide ; 3-Benzyl-6-trifluoromethyl-7-sulfamoyl-3,4-dihydro-1,2,4-
benzothiadiazine, 1,1-dioxide ; 6-Trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine, 1,1-dioxide ; Aprinox ; BHFT ; BL H368 ; BRN 0373316 ; Be 724-A ; Bendrofluazide ; Benuron ; Benzylrodiuran ; Berkozide ; Centyl ; Corzide ; Intolex ; Livesan ; Naturetin .