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| CAS No.: | 739366-20-2 |
|---|---|
| Name: | Anagliptin |
| Molecular Structure: | |
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| Formula: | C19H25N7O2 |
| Molecular Weight: | 383.453 |
| Synonyms: | N-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-methyl-propyl]-2-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxamide;Anagliptin; |
| Density: | 1.33±0.1 g/cm3(Predicted) |
| Melting Point: | 115-119°C |
| Solubility: | (0.25 g/L) (25 oC) |
| Appearance: | Off-White Solid |
| PSA: | 118.91000 |
| LogP: | 1.55388 |
Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction. It also attenuates atherosclerosis in male apolipoprotein E-deficient mice.