CAS No.74469-00-4,Amoxicillin-Potassium Clavulanate Combination Suppliers

Products Categories

Pharmaceutical (9)
Organic Chemicals (2)
Others (1)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	74469-00-4
Name:	Amoxicillin-Potassium Clavulanate Combination

Formula:	C₁₆H₁₉N₃O₅S•C₈H₉NO₅•K
Molecular Weight:	603.72
Synonyms:	Amoxicillin-Potassium Clavulanate Combination
Boiling Point:	743.2°C at 760 mmHg
Flash Point:	403.3°C
Safety:	Moderately toxic by some routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x, NO_x, and K₂O.
PSA:	248.16000
LogP:	-1.43960

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:13 Page 1 of 1 1

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 74469-00-4

Chemistry

Molecule structure of Augmentin (CAS NO.74469-00-4) :

IUPAC Name: potassium ; (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ; (3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-
carboxylate
Molecular Weight: 602.65528 g/mol
Molecular Formula: C₂₄H₂₇KN₄O₁₀S
Boiling Point: 743.2 °C at 760 mmHg
Flash Point: 403.3 °C
Vapour Pressure: 3.39E-23 mmHg at 25°C
Enthalpy of Vaporization: 113.73 kJ/mol
H-Bond Donor: 5
H-Bond Acceptor: 11
Rotatable Bond Count: 6
Tautomer Count: 4
MonoIsotopic Mass: 602.108496
Topological Polar Surface Area: 223
Heavy Atom Count: 40
Complexity: 919
Defined Atom StereoCenter Count: 5
Undefined Atom StereoCenter Count: 1
Defined Bond StereoCenter Count: 1
Covalently-Bonded Unit Count: 3
Isomeric SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)C.C1[C@@H]2N(C1=O)C(/C(=C/CO)/O2)C(=O)[O-].[K+]
InChI: InChI=1S/C16H19N3O5S.C8H9NO5.K/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);1,6-7,10H,2-3H2,(H,12,13);/q;;+1/p-1/b;4-1-;/t9-,10-,11+,14-;6-,7;/m11./s1
InChIKey: DWHGNUUWCJZQHO-VXMVAJKNSA-M

History

The Augmentin (CAS NO.74469-00-4) was invented around 1977/78 by British scientists working at Beecham, which filed for US patent protection for the drug combination in 1979. US patent 4441609 was granted in 1984.

Uses

The Augmentin (CAS NO.74469-00-4) acid combination is used in veterinary. The preparation for veterinary use is commonly marketed under the trade names Clavaseptin, and Clavamox. It is also used in the treatment of, among other infections, periodontitis in dogs and skin infections in cats. Augmentin acid is banned from use in domestic-food animals (cattle, swine, etc.) in both the US and Europe.

Toxicity Data With Reference

1.	ipr-rat LD50:2774 mg/kg	NKRZAZ Chemotherapy (Tokyo). 31 (Suppl 2)(1983),113.
2.	scu-rat LD50:3487 mg/kg	NKRZAZ Chemotherapy (Tokyo). 31 (Suppl 2)(1983),113.
3.	ipr-mus LD50:3925 mg/kg	NKRZAZ Chemotherapy (Tokyo). 31 (Suppl 2)(1983),113.
4.	scu-mus LD50:6433 mg/kg	NKRZAZ Chemotherapy (Tokyo). 31 (Suppl 2)(1983),113.

Safety Profile

Moderately toxic by some routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x, NO_x, and K₂O.

Specification

The Augmentin (CAS NO.74469-00-4) is also called Amocla ; Amoclan ; Amoclav ; Amoxicillin and clavulanate potassium ;
Amoxicillin mixed with potassium clavulanate (2:1) ; Amoxicillin mixture with Clavulanate potassium ; Amoxsiklav ; Ancla ; Augmentan ; Augmentin '125' ; Augmentin '200' ; Augmentin '250' ; Augmentin '400' ; Augmentin '500' ; Augmentin '875' ; Augmentin (antibiotic) ; Augmentin ES-600 ; Augmentin XR ; Augmentine ; Auspilic ; BRL 25000 ; BRL 25000A ; BRL 25000G ; Clamentin ; Clamobit ; Clavamox ; Clavinex ; Clavoxilin Plus ; Clavulin ; Clavumox ; Eumetinex ; Kmoxilin ; Potassium clavulanate mixed with amoxicillin (1:2) ; Spectramox ; Viaclav ; Xiclav . Liquid Augmentin (CAS NO.74469-00-4) must be refrigerated to maintain effectiveness.