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74790-08-2

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Basic Information
CAS No.: 74790-08-2
Name: [cyclohexane-1,1-diylbis(methylamine)-N,N'][sulphato(2-)-O,O']platinum
Molecular Structure:
Molecular Structure of 74790-08-2 ([cyclohexane-1,1-diylbis(methylamine)-N,N'][sulphato(2-)-O,O']platinum)
Formula: C8H18N2O4PtS
Molecular Weight: 433.388
Synonyms: Spiroplatin;
Density: g/cm3
Boiling Point: 198.8°Cat760mmHg
Flash Point: 83.9°C
Safety: Poison by intravenous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and SOx.
PSA: 140.68000
LogP: 1.99520
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Chemistry

IUPAC  Name: [1-(Azanidylmethyl)cyclohexyl]methylazanide; platinum(2+); sulfuric acid 
Molecular Formula: C8H18N2O4PtS
Molecular Weight: 433.43
Freely Rotating Bonds: 4
Polar Surface Area: 24.06 Å2
Flash Point: 83.9 °C
Enthalpy of Vaporization: 43.5 kJ/mol
Boiling Point: 198.8 °C at 760 mmHg
Vapour Pressure: 0.353 mmHg at 25°C 
The Cas Register Number of Spiroplatin is 74790-08-2.The chemical synonyms of Spiroplatin (CAS NO.74790-08-2) are (Cyclohexane-1,1-diylbis(methylamine)-N,N')(sulphato(2-)-O,O')platinum ; cis-(1,1-Cyclohexanebis(methylamine))(sulfato)platinum ; Platinum, (1,1-cyclohexanedimethanamine-N,N')(sulfato(2-)-O,O')-, (SP-4-2)- ; Spiroplatin .The molecular structure of  Spiroplatin (CAS NO.74790-08-2) is.

Uses

 Spiroplatin (CAS NO.74790-08-2) is used as pharmaceutical intermediate.

Toxicity Data With Reference

1.    

mmo-smc 100 µmol/L

     MUREAV    Mutation Research. 198 (1988),69.
2.    

sce-ham:lng 21 µmol/L

     EJCAAH    European Journal of Cancer. 25 (1989),27.
3.    

ivn-rat LD50:4 mg/kg

     EJCODS    European Journal of Cancer and Clinical Oncology. 20 (1984),1087.
4.    

ipr-mus LD50:13 mg/kg

     EJCODS    European Journal of Cancer and Clinical Oncology. 20 (1984),1087.
5.    

ivn-mus LD50:8900 µg/kg

     EJCODS    European Journal of Cancer and Clinical Oncology. 20 (1984),1087.

Safety Profile

Poison by intravenous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and SOx.