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Basic Information
| CAS No.: | 7542-37-2 |
|---|---|
| Name: | paromomycin |
| Article Data: | 3 |
| Cas Database | |
| Molecular Structure: | |
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| Formula: | C23H45 N5 O14 |
| Molecular Weight: | 615.635 |
| Synonyms: | D-Streptamine,O-2-amino-2-deoxy-a-D-glucopyranosyl-(1®4)-O-[O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(1®3)-b-D-ribofuranosyl-(1®5)]-2-deoxy-; Hydroxymycin (6CI); Streptamine, O-2,6-diamino-2,6-dideoxy-b-L-idopyranosyl-(1®3)-O-b-D-ribofuranosyl-(1®5)-O-[2-amino-2-deoxy-a-D-glucopyranosyl-(1®4)]-2-deoxy- (8CI); Zygomycin A1 (7CI); Aminosidin;Aminosidine; Aminosidine I; Amminosidin; Antibiotic 2230D; Antibiotic 503-3;Antibiotic SF 767B; Catenulin; Crestomycin; Gabbromicina; Gabbromycin;Gabromycin; Humycin; Monomycin A; Neomycin E; Paromomycin; Paromomycin I;Paromomycine; Paucimycin; Quintomycin C; R 400 |
| Density: | 1.64g/cm3 |
| Boiling Point: | 939.8ºC at 760 mmHg |
| Flash Point: | 522.2ºC |
| Safety: | Moderately toxic by ingestion, intramuscular, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx. |
| PSA: | 347.32000 |
| LogP: | -5.36020 |
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paromomycin
Toxicity Data With Reference
| 1. | orl-rat LD50:21,620 mg/kg | NKRZAZ Chemotherapy (Tokyo). 16 (1968),124. | ||
| 2. | scu-rat LD50:1010 mg/kg | ANTCAO Antibiotics and Chemotherapy. 12 (1962),243. | ||
| 3. | ims-rat LD50:1200 mg/kg | NKRZAZ Chemotherapy (Tokyo). 16 (1968),124. | ||
| 4. | orl-mus LD50:2275 mg/kg | 85ERAY Antibiotics: Origin, Nature, and Properties. 1 (1978),674. | ||
| 5. | ipr-mus LD50:930 mg/kg | 85FZAT Index of Antibiotics from Actinomycetes Umezawa, H., et al., eds.,Tokyo, Japan.: University of Tokyo Press,1967,332. |
Safety Profile
Moderately toxic by ingestion, intramuscular, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.