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Basic Information
| CAS No.: | 79-64-1 |
|---|---|
| Name: | DIMETHISTERONE |
| Molecular Structure: | |
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| Formula: | C23H32 O2 |
| Molecular Weight: | 340.506 |
| Synonyms: | Androst-4-en-3-one,17b-hydroxy-6a-methyl-17-(1-propynyl)-(7CI,8CI); Testosterone, 6a-methyl-17-(1-propynyl)- (6CI); 17b-Hydroxy-6a-methyl-17-(1-propynyl)androst-4-en-3-one; 6a,21-Dimethyl-17-ethynyl-17b-hydroxyandrost-4-en-3-one; 6a,21-Dimethylethisterone; 6a-Methyl-17-(1-propynyl)testosterone;6a-Methyl-17a-propynyltestosterone;Dimethisteron; Dimethisterone; Lutogan; P-5048; Secrosteron |
| Density: | 1.11g/cm3 |
| Melting Point: | 102° |
| Boiling Point: | 479°C at 760 mmHg |
| Flash Point: | 203.5°C |
| Safety: | Mildly toxic by ingestion. Questionable carcinogen. Experimental teratogenic and reproductive effects. A steroid used as a progestin and in the treatment of menstrual disorders. When heated to decomposition it emits acrid smoke and irritating fumes. |
| PSA: | 37.30000 |
| LogP: | 4.51870 |
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DIMETHISTERONE
Toxicity Data With Reference
| 1. | orl-mus LD50:7650 mg/kg | MEIEDD Merck Index. 10 (1983),469. |
Consensus Reports
IARC Cancer Review: Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 21 ,1979,p. 377.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .
Safety Profile
Mildly toxic by ingestion. Questionable carcinogen. Experimental teratogenic and reproductive effects. A steroid used as a progestin and in the treatment of menstrual disorders. When heated to decomposition it emits acrid smoke and irritating fumes.